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Plasma Lipoproteins as Mediators of the Oxidative Stress Induced by UV Light in Human Skin : A Review of Biochemical and Biophysical Studies on Mechanisms of Apolipoprotein Alteration, Lipid Peroxidation, and Associated Skin Cell Responses
المؤلفون المشاركون
Mazière, Jean-Claude
Morlière, Patrice
Filipe, Paulo
Patterson, Larry K.
Santus, R.
Freitas, João Pedro
Silva, João N.
المصدر
Oxidative Medicine and Cellular Longevity
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-11، 11ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-04-23
دولة النشر
مصر
عدد الصفحات
11
التخصصات الرئيسية
العلوم الطبيعية والحياتية (متداخلة التخصصات)
الأحياء
الملخص EN
There are numerous studies concerning the effect of UVB light on skin cells but fewer on other skin components such as the interstitial fluid.
This review highlights high-density lipoprotein (HDL) and low-density lipoprotein (LDL) as important targets of UVB in interstitial fluid.
Tryptophan residues are the sole apolipoprotein residues absorbing solar UVB.
The UVB-induced one-electron oxidation of Trp produces •Trp and O2•- radicals which trigger lipid peroxidation.
Immunoblots from buffered solutions or suction blister fluid reveal that propagation of photooxidative damage to other residues such as Tyr or disulfide bonds produces intra- and intermolecular bonds in apolipoproteins A-I, A-II, and B100.
Partial repair of phenoxyl tyrosyl radicals (TyrO•) by α-tocopherol is observed with LDL and HDL on millisecond or second time scales, whereas limited repair of α-tocopherol by carotenoids occurs in only HDL.
More effective repair of Tyr and α-tocopherol is observed with the flavonoid, quercetin, bound to serum albumin, but quercetin is less potent than new synthetic polyphenols in inhibiting LDL lipid peroxidation or restoring α-tocopherol.
The systemic consequences of HDL and LDL oxidation and the activation and/or inhibition of signalling pathways by oxidized LDL and their ability to enhance transcription factor DNA binding activity are also reviewed.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Filipe, Paulo& Morlière, Patrice& Silva, João N.& Mazière, Jean-Claude& Patterson, Larry K.& Freitas, João Pedro…[et al.]. 2013. Plasma Lipoproteins as Mediators of the Oxidative Stress Induced by UV Light in Human Skin : A Review of Biochemical and Biophysical Studies on Mechanisms of Apolipoprotein Alteration, Lipid Peroxidation, and Associated Skin Cell Responses. Oxidative Medicine and Cellular Longevity،Vol. 2013, no. 2013, pp.1-11.
https://search.emarefa.net/detail/BIM-460410
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Filipe, Paulo…[et al.]. Plasma Lipoproteins as Mediators of the Oxidative Stress Induced by UV Light in Human Skin : A Review of Biochemical and Biophysical Studies on Mechanisms of Apolipoprotein Alteration, Lipid Peroxidation, and Associated Skin Cell Responses. Oxidative Medicine and Cellular Longevity No. 2013 (2013), pp.1-11.
https://search.emarefa.net/detail/BIM-460410
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Filipe, Paulo& Morlière, Patrice& Silva, João N.& Mazière, Jean-Claude& Patterson, Larry K.& Freitas, João Pedro…[et al.]. Plasma Lipoproteins as Mediators of the Oxidative Stress Induced by UV Light in Human Skin : A Review of Biochemical and Biophysical Studies on Mechanisms of Apolipoprotein Alteration, Lipid Peroxidation, and Associated Skin Cell Responses. Oxidative Medicine and Cellular Longevity. 2013. Vol. 2013, no. 2013, pp.1-11.
https://search.emarefa.net/detail/BIM-460410
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-460410
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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