Integrating Imaging Data into Predictive Biomathematical and Biophysical Models of Cancer
المؤلف
المصدر
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-12، 12ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-12-26
دولة النشر
مصر
عدد الصفحات
12
التخصصات الرئيسية
الملخص EN
While there is a mature literature on biomathematical and biophysical modeling in cancer, many of the existing approaches are not of clinical utility, as they require input data that are extremely difficult to obtain in an intact organism, and/or require a large number of assumptions on the free parameters included in the models.
Thus, there has only been very limited application of such models to solve problems of clinical import.
More recently, however, there has been increased activity at the interface of quantitative, noninvasive imaging data, and tumor mathematical modeling.
In addition to reporting on bulk tumor morphology and volume, emerging imaging techniques can quantitatively report on for example tumor vascularity, glucose metabolism, cell density and proliferation, and hypoxia.
In this paper, we first motivate the problem of predicting therapy response by highlighting some (acknowledged) shortcomings in existing methods.
We then provide introductions to a number of representative quantitative imaging methods and describe how they are currently (and potentially can be) used to initialize and constrain patient specific mathematical and biophysical models of tumor growth and treatment response, thereby increasing the clinical utility of such approaches.
We conclude by highlighting some of the exciting research directions when one integrates quantitative imaging and tumor modeling.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Yankeelov, Thomas E.. 2012. Integrating Imaging Data into Predictive Biomathematical and Biophysical Models of Cancer. ISRN Biomathematics،Vol. 2012, no. 2012, pp.1-12.
https://search.emarefa.net/detail/BIM-460562
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Yankeelov, Thomas E.. Integrating Imaging Data into Predictive Biomathematical and Biophysical Models of Cancer. ISRN Biomathematics No. 2012 (2012), pp.1-12.
https://search.emarefa.net/detail/BIM-460562
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Yankeelov, Thomas E.. Integrating Imaging Data into Predictive Biomathematical and Biophysical Models of Cancer. ISRN Biomathematics. 2012. Vol. 2012, no. 2012, pp.1-12.
https://search.emarefa.net/detail/BIM-460562
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-460562
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر