Biologics in Paediatric Crohn's Disease
المؤلفون المشاركون
Catto-Smith, Anthony G.
Alex, George
Gouldthorpe, Oliver
المصدر
Gastroenterology Research and Practice
العدد
المجلد 2011، العدد 2011 (31 ديسمبر/كانون الأول 2011)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2011-11-17
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Crohn's disease affects increasing numbers of children worldwide.
Generally, childhood-onset disease runs a more severe course than in adults and has a greater impact on quality of life.
Therapy in children must take account of a different set of risks for toxicity compared to adults, but also to their longevity.
Biologic drugs present remarkable advantages in terms of disease control for children, especially in those whose disease cannot be controlled with conventional therapies, but their long-term risks are still being assessed.
Data regarding biologic use in children is limited and mostly amounts to case series, but results have been promising, both in terms of controlling disease activity and improving growth parameters.
Adverse reactions are infrequent in the short term, but loss of response is a long-term problem, particularly in children.
More information is needed about very long term risks.
Infliximab and adalimumab are the most studied agents in children, while there is relatively limited data on certolizumab and natalizumab.
Further collection of data on these agents is still needed, but this should not restrict access to these agents for children in whom no other agent is effective.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Gouldthorpe, Oliver& Catto-Smith, Anthony G.& Alex, George. 2011. Biologics in Paediatric Crohn's Disease. Gastroenterology Research and Practice،Vol. 2011, no. 2011, pp.1-10.
https://search.emarefa.net/detail/BIM-460587
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Gouldthorpe, Oliver…[et al.]. Biologics in Paediatric Crohn's Disease. Gastroenterology Research and Practice No. 2011 (2011), pp.1-10.
https://search.emarefa.net/detail/BIM-460587
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Gouldthorpe, Oliver& Catto-Smith, Anthony G.& Alex, George. Biologics in Paediatric Crohn's Disease. Gastroenterology Research and Practice. 2011. Vol. 2011, no. 2011, pp.1-10.
https://search.emarefa.net/detail/BIM-460587
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-460587
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر