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Moderation of Breastfeeding Effects on Adult Depression by Estrogen Receptor Gene Polymorphism
المؤلفون المشاركون
Salo, Johanna
Jokela, Markus
Lehtimäki, Terho
Merjonen, Päivi
Viikari, Jorma
Hintsanen, Mirka
Keltikangas-Järvinen, Liisa
Raitakari, Olli T.
المصدر
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-11-12
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الموضوعات
الملخص EN
Breastfeeding is known to benefit both the mother’s and the child’s health.
Our aim was to test the interactive effects between estrogen receptor 1 (ESR1) rs2234693 and breastfeeding when predicting the child’s later depression in adulthood.
A sample of 1209 boys and girls from the Young Finns Study were followed from childhood over 27 years up to age 30–45 years.
Adulthood depressive symptoms were self-reported by the participants using the Beck Depression Inventory.
Breastfeeding as well as several possibly confounding factors was reported by the parents in childhood or adolescence.
Breastfeeding tended to predict lower adult depression, while ESR1 rs2234693 was not associated with depression.
A significant interaction between breastfeeding and ESR1 was found to predict participants’ depression (P=.004) so that C/C genotype carriers who had not been breastfed had higher risk of depression than T-allele carriers (40.5% versus 13.0%) while there were no genotypic differences among those who had been breastfed.
In sex-specific analysis, this interaction was evident only among women.
We conclude that child’s genes and maternal behavior may interact in the development of child’s adult depression so that breastfeeding may buffer the inherited depression risk possibly associated with the C/C genotype of the ESR1 gene.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Merjonen, Päivi& Jokela, Markus& Salo, Johanna& Lehtimäki, Terho& Viikari, Jorma& Raitakari, Olli T.…[et al.]. 2012. Moderation of Breastfeeding Effects on Adult Depression by Estrogen Receptor Gene Polymorphism. Child Development Research،Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-460809
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Merjonen, Päivi…[et al.]. Moderation of Breastfeeding Effects on Adult Depression by Estrogen Receptor Gene Polymorphism. Child Development Research No. 2012 (2012), pp.1-8.
https://search.emarefa.net/detail/BIM-460809
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Merjonen, Päivi& Jokela, Markus& Salo, Johanna& Lehtimäki, Terho& Viikari, Jorma& Raitakari, Olli T.…[et al.]. Moderation of Breastfeeding Effects on Adult Depression by Estrogen Receptor Gene Polymorphism. Child Development Research. 2012. Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-460809
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-460809
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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