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Inhibitory Effect of NMDA Receptors in the Ventral Tegmental Area on Hormonal and Eating Behavior Responses to Stress in Rats
المؤلفون المشاركون
Ranjbaran, Mina
Baghlani, Kefayat
Khosravi, Maryam
Sahraei, Hedayat
Bourbour, Zahra
Sahraei, Mohammad
Hassantash, Seyedeh Maryam
Nasihatkon, Zohreh Sadat
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-08-07
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Background.
Stress and its consequences are among the causes of accidents.
Objective.
The effects of intraventral tegmental area (I-VTA) memantine on the plasma corticosterone and eating parameters disturbance induced by acute stress were investigated.
Methods.
Male Wistar rats (W: 250–300 g) were divided into control and experiential groups, each of which received memantine either intra-VTA or peripherally.
One week after bilateral cannulation, the rats received memantine (1 and 5 μg/Rat) five min before electroshock stress.
The other experimental groups received memantine (1 and 5 mg/kg) intraperitoneally 30 min before stress.
The control groups received saline or memantine but did not experience stress.
Food and water intake and plasma corticosterone level were recorded.
Results.
Results showed that stress decreases food intake but does not change water intake and increase in plasma corticosterone level.
Intraperitoneal memantine administration slightly inhibits the stress effects on food intake.
However, water intake and plasma corticosterone level were increased.
Intra-VTA memantine reduces the effects of stress on corticosterone and water intake.
Conclusion.
It could be concluded that inhibition of glutamate NMDA receptors in the VTA by memantine leads to the inhibition of the eating behavior parameters and plasma corticosterone level disturbance induced by stress in rats.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Nasihatkon, Zohreh Sadat& Khosravi, Maryam& Bourbour, Zahra& Sahraei, Hedayat& Ranjbaran, Mina& Hassantash, Seyedeh Maryam…[et al.]. 2014. Inhibitory Effect of NMDA Receptors in the Ventral Tegmental Area on Hormonal and Eating Behavior Responses to Stress in Rats. Behavioural Neurology،Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-461111
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Nasihatkon, Zohreh Sadat…[et al.]. Inhibitory Effect of NMDA Receptors in the Ventral Tegmental Area on Hormonal and Eating Behavior Responses to Stress in Rats. Behavioural Neurology No. 2014 (2014), pp.1-6.
https://search.emarefa.net/detail/BIM-461111
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Nasihatkon, Zohreh Sadat& Khosravi, Maryam& Bourbour, Zahra& Sahraei, Hedayat& Ranjbaran, Mina& Hassantash, Seyedeh Maryam…[et al.]. Inhibitory Effect of NMDA Receptors in the Ventral Tegmental Area on Hormonal and Eating Behavior Responses to Stress in Rats. Behavioural Neurology. 2014. Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-461111
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-461111
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
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