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Noninterventional Open-Label Trial Investigating the Efficacy and Safety of Ectoine Containing Nasal Spray in Comparison with Beclomethasone Nasal Spray in Patients with Allergic Rhinitis
المؤلفون المشاركون
Sonnemann, Uwe
Möller, Marcus
Bilstein, Andreas
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-12، 12ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-05-28
دولة النشر
مصر
عدد الصفحات
12
التخصصات الرئيسية
الملخص EN
Objectives.
The current study aimed to compare the efficacy and safety of a classical anti-inflammatory beclomethasone nasal spray in comparison to a physic-chemical stabilizing ectoine containing nasal spray in the treatment of allergic rhinitis.
Design and Methods.
This was a noninterventional, open-label, observational trial investigating the effects of beclomethasone or ectoine nasal spray on nasal symptoms and quality of life.
Over a period of 14 days, patients were asked to daily document their symptoms.
Efficacy and tolerability were assessed by both physicians and patients.
Results.
Both treatments resulted in a significant decrease of TNSS values.
An equivalence test could not confirm the noninferiority of ectoine treatment in comparison with beclomethasone treatment.
Although clear symptom reduction was achieved with the ectoine products, the efficacy judgment showed possible advantages for the beclomethasone group.
Importantly, tolerability results were comparably good in both groups, and a very low number of adverse events supported this observation.
Both treatments resulted in a clear improvement in the quality of life as assessed by a questionnaire answered at the beginning and at the end of the trial.
Conclusion.
Taken together, it was shown that allergic rhinitis can be safely and successfully treated with beclomethasone and also efficacy and safety were shown for ectoine nasal spray.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Sonnemann, Uwe& Möller, Marcus& Bilstein, Andreas. 2014. Noninterventional Open-Label Trial Investigating the Efficacy and Safety of Ectoine Containing Nasal Spray in Comparison with Beclomethasone Nasal Spray in Patients with Allergic Rhinitis. Journal of Allergy،Vol. 2014, no. 2014, pp.1-12.
https://search.emarefa.net/detail/BIM-461397
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Sonnemann, Uwe…[et al.]. Noninterventional Open-Label Trial Investigating the Efficacy and Safety of Ectoine Containing Nasal Spray in Comparison with Beclomethasone Nasal Spray in Patients with Allergic Rhinitis. Journal of Allergy No. 2014 (2014), pp.1-12.
https://search.emarefa.net/detail/BIM-461397
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Sonnemann, Uwe& Möller, Marcus& Bilstein, Andreas. Noninterventional Open-Label Trial Investigating the Efficacy and Safety of Ectoine Containing Nasal Spray in Comparison with Beclomethasone Nasal Spray in Patients with Allergic Rhinitis. Journal of Allergy. 2014. Vol. 2014, no. 2014, pp.1-12.
https://search.emarefa.net/detail/BIM-461397
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-461397
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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