Serum Resistin and Insulin-Like Growth Factor-1 Levels in Patients with Hypothyroidism and Hyperthyroidism
المؤلفون المشاركون
Ozpacaci, Tevfik
Eke Koyuncu, Ceren
Turkmen Yildirmak, Sembol
Ozbanazi, Yüksel Gülen
Cakmak, Mustafa
Temizel, Mustafa
Gunel, Pinar
المصدر
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-02-24
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Introduction.
The aim of this study was to evaluate the serum levels of resistin and insulin-like growth factor-1 (IGF-1) and and also the potential relationship between thyroid function and levels of resistin and IGF-1 in hypothyroid and hyperthyroid patients.
Methods.
Fifteen cases of hypothyroid (HT), 16 of subclinically hypothyroid (SCHT), 15 of hyperthyroid (HrT), 15 of subclinically hyperthyroid (SCHrT), and 17 healthy individuals have been included in the study.
Serum resistin levels were measured using enzyme-linked immunosorbent assay and IGF-1 and thyroid stimulating hormone (TSH) levels by chemiluminescence method.
Results.
Resistin levels in total HT group were significantly higher than in controls (12.66 ± 6.04 and 8.45 ± 2.90 ng/mL, resp.).
In SCHrT subgroup resistin levels were significantly higher than those of controls (14.88 ± 7.73 and 8.45 ± 2.90 ng/mL, resp.).
IGF-1 levels were significantly lower in total HT than in total HrT and control groups (117.22 ± 52.03, 155.17 ± 51.67, and 184.00 ± 49.73 ng/mL, resp.).
Furthermore IGF-1 levels in HT subgroup were significantly lower compared to controls (123.70 ± 44.03 and 184 ± 49.73 ng/mL, resp.).
In SCHT subgroup IGF-1 levels were significantly lower than those of control and SCHrT groups (111.11 ± 59.35, 184.00 ± 49.73, and 166.60 ± 47.87 ng/mL, resp.).
There were significant correlations between IGF-1 and TSH in HT subgroup and between resistin and TSH in total HrT group.
Conclusion.
It was concluded that increased resistin levels are directly related to thyroid dysfunction, and GH/IGF-1 axis is influenced in clinically or subclinically hypothyroidism patients.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Eke Koyuncu, Ceren& Turkmen Yildirmak, Sembol& Temizel, Mustafa& Ozpacaci, Tevfik& Gunel, Pinar& Cakmak, Mustafa…[et al.]. 2013. Serum Resistin and Insulin-Like Growth Factor-1 Levels in Patients with Hypothyroidism and Hyperthyroidism. Journal of Thyroid Research،Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-462079
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Eke Koyuncu, Ceren…[et al.]. Serum Resistin and Insulin-Like Growth Factor-1 Levels in Patients with Hypothyroidism and Hyperthyroidism. Journal of Thyroid Research No. 2013 (2013), pp.1-6.
https://search.emarefa.net/detail/BIM-462079
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Eke Koyuncu, Ceren& Turkmen Yildirmak, Sembol& Temizel, Mustafa& Ozpacaci, Tevfik& Gunel, Pinar& Cakmak, Mustafa…[et al.]. Serum Resistin and Insulin-Like Growth Factor-1 Levels in Patients with Hypothyroidism and Hyperthyroidism. Journal of Thyroid Research. 2013. Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-462079
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-462079
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر