Efficacy and Safety of Iguratimod for the Treatment of Rheumatoid Arthritis
المؤلفون المشاركون
Li, Jiangtao
Shi, Guixiu
Lu, Yanrong
Yang, Nanping
Mao, Hejuan
Chen, Shuo
Liang, Yan
المصدر
Clinical and Developmental Immunology
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-16، 16ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-11-26
دولة النشر
مصر
عدد الصفحات
16
التخصصات الرئيسية
الملخص EN
All randomized controlled trials (RCTs) of iguratimod for rheumatoid arthritis (RA) to assess its efficacy and safety are included in this paper.
The Review Manager software was used for meta-analysis to assess risk bias of the studies included, and GRADE profiler software was used for the evidence quality of the studies included.
Four RCTs involving 1407 patients with RA were included.
Meta-analyses showed that, after 24-week therapy, ACR20, tender joint count, swollen joint count, rest pain, physician and patient global assessment of disease activity, HAQ score, ESR, and CRP in iguratimod group were better than those in placebo group and that the difference between those of iguratimod group and those of other DMARDs (MTX and SASP) group was not significant.
GRADE evidence classification of the studies included was moderate.
Iguratimod for RA had few adverse events, and its efficacy and safety were the same as those of MTX and SASP for RA.
The results of this systematic review suggest that more high-quality and large-scaled RCTs were needed to determine the efficacy of iguratimod for RA and whether iguratimod is as effective as other DMARDs besides MTX and SASP.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Li, Jiangtao& Mao, Hejuan& Liang, Yan& Lu, Yanrong& Chen, Shuo& Yang, Nanping…[et al.]. 2013. Efficacy and Safety of Iguratimod for the Treatment of Rheumatoid Arthritis. Clinical and Developmental Immunology،Vol. 2013, no. 2013, pp.1-16.
https://search.emarefa.net/detail/BIM-462468
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Li, Jiangtao…[et al.]. Efficacy and Safety of Iguratimod for the Treatment of Rheumatoid Arthritis. Clinical and Developmental Immunology No. 2013 (2013), pp.1-16.
https://search.emarefa.net/detail/BIM-462468
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Li, Jiangtao& Mao, Hejuan& Liang, Yan& Lu, Yanrong& Chen, Shuo& Yang, Nanping…[et al.]. Efficacy and Safety of Iguratimod for the Treatment of Rheumatoid Arthritis. Clinical and Developmental Immunology. 2013. Vol. 2013, no. 2013, pp.1-16.
https://search.emarefa.net/detail/BIM-462468
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-462468
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر