![](/images/graphics-bg.png)
A Quest to Identify Prostate Cancer Circulating Biomarkers with a Bench-to-Bedside Potential
المؤلفون المشاركون
Hlatky, Lynn
Girdhani, Swati
Batra, Jaspreet Singh
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-12، 12ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-03-12
دولة النشر
مصر
عدد الصفحات
12
التخصصات الرئيسية
الملخص EN
Prostate cancer (PCA) is a major health concern in current times.
Ever since prostate specific antigen (PSA) was introduced in clinical practice almost three decades ago, the diagnosis and management of PCA have been revolutionized.
With time, concerns arose as to the inherent shortcomings of this biomarker and alternatives were actively sought.
Over the past decade new PCA biomarkers have been identified in tissue, blood, urine, and other body fluids that offer improved specificity and supplement our knowledge of disease progression.
This review focuses on superiority of circulating biomarkers over tissue biomarkers due to the advantages of being more readily accessible, minimally invasive (blood) or noninvasive (urine), accessible for sampling on regular intervals, and easily utilized for follow-up after surgery or other treatment modalities.
Some of the circulating biomarkers like PCA3, IL-6, and TMPRSS2-ERG are now detectable by commercially available kits while others like microRNAs (miR-21, -221, -141) and exosomes hold potential to become available as multiplexed assays.
In this paper, we will review some of these potential candidate circulating biomarkers that either individually or in combination, once validated with large-scale trials, may eventually get utilized clinically for improved diagnosis, risk stratification, and treatment.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Batra, Jaspreet Singh& Girdhani, Swati& Hlatky, Lynn. 2014. A Quest to Identify Prostate Cancer Circulating Biomarkers with a Bench-to-Bedside Potential. Journal of Biomarkers،Vol. 2014, no. 2014, pp.1-12.
https://search.emarefa.net/detail/BIM-463388
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Batra, Jaspreet Singh…[et al.]. A Quest to Identify Prostate Cancer Circulating Biomarkers with a Bench-to-Bedside Potential. Journal of Biomarkers No. 2014 (2014), pp.1-12.
https://search.emarefa.net/detail/BIM-463388
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Batra, Jaspreet Singh& Girdhani, Swati& Hlatky, Lynn. A Quest to Identify Prostate Cancer Circulating Biomarkers with a Bench-to-Bedside Potential. Journal of Biomarkers. 2014. Vol. 2014, no. 2014, pp.1-12.
https://search.emarefa.net/detail/BIM-463388
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-463388
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
![](/images/ebook-kashef.png)
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
![](/images/kashef-image.png)