Paternal Occupational Exposure to Endocrine-Disrupting Chemicals as a Risk Factor for Leukaemia in Children : A Case-Control Study from the North of England
المؤلفون المشاركون
Baxter, Lucy R.
Parker, Louise
Pearce, Mark S.
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-07-16
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Occupations with exposures to a variety of chemicals, including those thought to be potential endocrine disruptors, have been associated with an increased risk of leukaemia in offspring.
We investigated whether an association exists between paternal occupations at birth involving such exposures and risk of leukaemia in offspring.
Cases (n=958) were matched, on sex and year of birth, to controls from two independent sources, one other cancers, one cancer-free live births.
Paternal occupations at birth were classified, using an occupational exposure matrix, as having “very unlikely,” “possible,” or “likely” exposure to six groups of potential endocrine-disrupting chemicals.
There was a significantly increased risk of acute nonlymphocytic leukaemia (ANLL) for polychlorinated organic compounds (OR 1.95, 95% CI 1.08–3.54) only in comparison with cancer-free controls, and for phthalates (OR 1.61, 95% CI 1.00–2.61) only with registry controls.
A number of other, including inverse, associations were seen, but limited to one control group only.
No associations were seen with likely paternal exposure to heavy metals.
The associations identified in this study require further investigation, with better exposure and potential confounding (for example maternal variables) information, to evaluate the likelihood of true associations to assess whether they are real or due to chance.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Pearce, Mark S.& Baxter, Lucy R.& Parker, Louise. 2014. Paternal Occupational Exposure to Endocrine-Disrupting Chemicals as a Risk Factor for Leukaemia in Children : A Case-Control Study from the North of England. Advances in Epidemiology،Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-463431
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Pearce, Mark S.…[et al.]. Paternal Occupational Exposure to Endocrine-Disrupting Chemicals as a Risk Factor for Leukaemia in Children : A Case-Control Study from the North of England. Advances in Epidemiology No. 2014 (2014), pp.1-7.
https://search.emarefa.net/detail/BIM-463431
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Pearce, Mark S.& Baxter, Lucy R.& Parker, Louise. Paternal Occupational Exposure to Endocrine-Disrupting Chemicals as a Risk Factor for Leukaemia in Children : A Case-Control Study from the North of England. Advances in Epidemiology. 2014. Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-463431
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-463431
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر