![](/images/graphics-bg.png)
Neonauclea reticulata (Havil.) Merr Stimulates Skin Regeneration after UVB Exposure via ROS Scavenging and Modulation of the MAPKMMPsCollagen Pathway
المؤلفون المشاركون
Chen, Chien-Wen
Chen, Hsin-Chun
Wang, Ssu-Meng
Chiang, Hsiu-Mei
Chiu, Hua-Hsien
Wen, Kuo-Ching
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-06-15
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
In this study, we investigated whether the protective effects of Neonauclea reticulata water extract against ultraviolet B (UVB) irradiation in human skin fibroblast cell cultures (Hs68) are governed by its ability to protect against oxidative stress and expression of matrix metalloproteinases (MMPs).
We found that Neonauclea reticulata extract exhibited DPPH scavenging activity and inhibited AAPH-induced haemolysis of erythrocytes in a dose- and time-dependent manner.
We also found that pretreatment of fibroblasts with Neonauclea reticulata water extract resulted in markedly lower levels of MMP-1, -3, and -9 expressions.
Furthermore, our results indicate that Neonauclea reticulata extract inhibits the expression of MMPs by inhibiting ERK, JNK, and p38 phosphorylation.
Our results also demonstrate that treatment with Neonauclea reticulata extract protects against UVB-induced depletion of collagen.
In addition, Neonauclea reticulata extract did not have a cytotoxic effect.
These findings indicate that the antioxidant activity of Neonauclea reticulata extract resulted in inhibition of MMP-1, -3, and -9 expressions and in increased levels of collagen activity.
Our results suggest that Neonauclea reticulata extract can protect against photoaging.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Chiang, Hsiu-Mei& Chen, Hsin-Chun& Chiu, Hua-Hsien& Chen, Chien-Wen& Wang, Ssu-Meng& Wen, Kuo-Ching. 2013. Neonauclea reticulata (Havil.) Merr Stimulates Skin Regeneration after UVB Exposure via ROS Scavenging and Modulation of the MAPKMMPsCollagen Pathway. Evidence-Based Complementary and Alternative Medicine،Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-463588
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Chiang, Hsiu-Mei…[et al.]. Neonauclea reticulata (Havil.) Merr Stimulates Skin Regeneration after UVB Exposure via ROS Scavenging and Modulation of the MAPKMMPsCollagen Pathway. Evidence-Based Complementary and Alternative Medicine No. 2013 (2013), pp.1-9.
https://search.emarefa.net/detail/BIM-463588
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Chiang, Hsiu-Mei& Chen, Hsin-Chun& Chiu, Hua-Hsien& Chen, Chien-Wen& Wang, Ssu-Meng& Wen, Kuo-Ching. Neonauclea reticulata (Havil.) Merr Stimulates Skin Regeneration after UVB Exposure via ROS Scavenging and Modulation of the MAPKMMPsCollagen Pathway. Evidence-Based Complementary and Alternative Medicine. 2013. Vol. 2013, no. 2013, pp.1-9.
https://search.emarefa.net/detail/BIM-463588
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-463588
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
![](/images/ebook-kashef.png)
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
![](/images/kashef-image.png)