Predictive and Prognostic Factors in Definition of Risk Groups in Endometrial Carcinoma
المؤلف
المصدر
ISRN Obstetrics and Gynecology
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-11-14
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Background.
The aim was to evaluate predictive and prognostic factors in a large consecutive series of endometrial carcinomas and to discuss pre- and postoperative risk groups based on these factors.
Material and Methods.
In a consecutive series of 4,543 endometrial carcinomas predictive and prognostic factors were analyzed with regard to recurrence rate and survival.
The patients were treated with primary surgery and adjuvant radiotherapy.
Two preoperative and three postoperative risk groups were defined.
DNA ploidy was included in the definitions.
Eight predictive or prognostic factors were used in multivariate analyses.
Results.
The overall recurrence rate of the complete series was 11.4%.
Median time to relapse was 19.7 months.
In a multivariate logistic regression analysis, FIGO grade, myometrial infiltration, and DNA ploidy were independent and statistically predictive factors with regard to recurrence rate.
The 5-year overall survival rate was 73%.
Tumor stage was the single most important factor with FIGO grade on the second place.
DNA ploidy was also a significant prognostic factor.
In the preoperative risk group definitions three factors were used: histology, FIGO grade, and DNA ploidy.
Conclusions.
DNA ploidy was an important and significant predictive and prognostic factor and should be used both in preoperative and postoperative risk group definitions.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Sorbe, Bengt. 2012. Predictive and Prognostic Factors in Definition of Risk Groups in Endometrial Carcinoma. ISRN Obstetrics and Gynecology،Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-463676
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Sorbe, Bengt. Predictive and Prognostic Factors in Definition of Risk Groups in Endometrial Carcinoma. ISRN Obstetrics and Gynecology No. 2012 (2012), pp.1-8.
https://search.emarefa.net/detail/BIM-463676
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Sorbe, Bengt. Predictive and Prognostic Factors in Definition of Risk Groups in Endometrial Carcinoma. ISRN Obstetrics and Gynecology. 2012. Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-463676
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-463676
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر