![](/images/graphics-bg.png)
A Randomised, Double-Blinded, Placebo-Controlled, Parallel Study of Vitamin D3 Supplementation with Different Schemes Based on Multiples of 25,000 IU Doses
المؤلفون المشاركون
Souberbielle, Jean-Claude
Faché, Werner
Cavalier, Etienne
المصدر
International Journal of Endocrinology
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-01-28
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Vitamin D (VTD) treatment is recommended in patients presenting different causes of diseases.
To treat these patients, physicians rely on the different available pharmaceutical forms present in their country.
Unfortunately, even in a given country, there is no consensus on the best way to treat the patients.
In Belgium, VTD is mostly prescribed as ampoules containing 25,000 IU of VTD.
In this randomised controlled study, we evaluated whether four therapeutic schemes using multiples of 25,000 IU of VTD according to basal vitamin D concentration were able to increase or maintain the 25(OH)D serum level above 30 ng/mL.
We randomized 175 subjects who received the drug (n=140) or placebo (n=35).
Total duration of the study was 12 weeks.
Doses ranged from 4167 to 1667 IU/day.
Blood sampling was performed at baseline and each 4 visits.
In the treated (placebo) subjects, mean 25(OH)D serum concentration was 18.7 (19.1) ng/mL at baseline and 31.5 (20.7) ng/mL at w-12.
At the end of the study, 57.1% of the subjects treated with VTD presented 25(OH)D serum concentration ≥30 ng/mL, whereas 94.3% were ≥20 ng/mL.
In conclusion, the doses administered were safe and increased or maintained the 25(OH)D concentration ≥20 ng/mL.
However, concentrations ≥30 ng/mL were only achieved in 57.1% of the subjects.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Cavalier, Etienne& Faché, Werner& Souberbielle, Jean-Claude. 2013. A Randomised, Double-Blinded, Placebo-Controlled, Parallel Study of Vitamin D3 Supplementation with Different Schemes Based on Multiples of 25,000 IU Doses. International Journal of Endocrinology،Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-463820
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Cavalier, Etienne…[et al.]. A Randomised, Double-Blinded, Placebo-Controlled, Parallel Study of Vitamin D3 Supplementation with Different Schemes Based on Multiples of 25,000 IU Doses. International Journal of Endocrinology No. 2013 (2013), pp.1-8.
https://search.emarefa.net/detail/BIM-463820
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Cavalier, Etienne& Faché, Werner& Souberbielle, Jean-Claude. A Randomised, Double-Blinded, Placebo-Controlled, Parallel Study of Vitamin D3 Supplementation with Different Schemes Based on Multiples of 25,000 IU Doses. International Journal of Endocrinology. 2013. Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-463820
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-463820
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
![](/images/ebook-kashef.png)
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
![](/images/kashef-image.png)