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Functional MRI Study of Working Memory Impairment in Patients with Symptomatic Carotid Artery Disease
المؤلفون المشاركون
Ma, Qingfeng
Shu, Hua
Zheng, Shasha
Zhang, Miao
Li, Kuncheng
Lu, Jie
Wang, Xiaoyi
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-02-20
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
The neuropsychological tests in patients with internal carotid artery (ICA) demonstrated cognitive deficits associated with frontal lobe dysfunction, but the pathophysiological mechanism of memory impairment is not fully understood.
This study evaluated relationship between degree of ICA stenosis and frontal activations induced by working memory (WM) task using fMRI.
The fMRI data of 21 patients with unilateral ICA stenosis (left/right, 11/10) and 21 controls were analyzed.
In comparison with controls, ICA patients demonstrated significant activations in middle frontal gyrus (MFG) bilaterally, particularly in left MFG.
In right ICA stenosis, there was slightly less MFG activation than that of controls.
Importantly, lower MFG activity was associated with higher stenosis of ipsilateral ICA.
For left ICA stenosis, weaker activation in left MFG was negatively correlated with degree of stenosis.
Similarly, for right ICA stenosis, there was a significant negative correlation between right ICA stenosis and weaker activation of right MFG.
Cognitive impairments in ICA stenosis were associated with frontal lobe dysfunctions.
Left ICA stenosis had worse WM impairments than right ICA stenosis, which was affected by the degree of stenosis.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Zheng, Shasha& Zhang, Miao& Wang, Xiaoyi& Ma, Qingfeng& Shu, Hua& Lu, Jie…[et al.]. 2014. Functional MRI Study of Working Memory Impairment in Patients with Symptomatic Carotid Artery Disease. BioMed Research International،Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-463822
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Zheng, Shasha…[et al.]. Functional MRI Study of Working Memory Impairment in Patients with Symptomatic Carotid Artery Disease. BioMed Research International No. 2014 (2014), pp.1-6.
https://search.emarefa.net/detail/BIM-463822
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Zheng, Shasha& Zhang, Miao& Wang, Xiaoyi& Ma, Qingfeng& Shu, Hua& Lu, Jie…[et al.]. Functional MRI Study of Working Memory Impairment in Patients with Symptomatic Carotid Artery Disease. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-463822
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-463822
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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