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Gastroesophageal Reflux Disease Relief in Patients Treated with Rabeprazole 20 mg versus Omeprazole 20 mg : A Meta-Analysis
المؤلفون المشاركون
المصدر
Gastroenterology Research and Practice
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-09-09
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Background.
Randomized controlled trials (RCTs) have been conducted comparing the efficacy of rabeprazole 20 mg or omeprazole 20 mg once daily for patients with erosive gastroesophageal reflux disease (GERD).
Until now, no study has synthesized all available data examining this issue.
Method.
Medline, Embase, and the Cochrane central register of controlled trials were searched (through December 2012).
Eligible RCTs recruited adults with erosive GERD and reported endoscopic and symptomatic relief rates at the last point of follow-up.
The effect of rabeprazole versus omeprazole was reported as relative risk (RR) of relief with a 95% confidence interval (CI).
Results.
The search identified 605 citations, and six RCTs containing 1,895 patients were eligible.
Endoscopic relief rates were not significantly different between rabeprazole 20 mg and omeprazole 20 mg in treatment trials of up to 8 weeks.
Heartburn relief rates were significantly different between the two groups for 8-week treatment trials.
Adverse events were not significantly different between the two groups for 8-week treatment trials.
Conclusion.
These data suggest that rabeprazole demonstrates a clinical advantage over omeprazole in symptomatic relief but no significant difference in endoscopic relief of erosive GERD for up to 8 weeks of treatment.
Rabeprazole and omeprazole were both tolerated by GERD patients.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Xia, X. M.& Wang, H.. 2013. Gastroesophageal Reflux Disease Relief in Patients Treated with Rabeprazole 20 mg versus Omeprazole 20 mg : A Meta-Analysis. Gastroenterology Research and Practice،Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-463852
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Xia, X. M.& Wang, H.. Gastroesophageal Reflux Disease Relief in Patients Treated with Rabeprazole 20 mg versus Omeprazole 20 mg : A Meta-Analysis. Gastroenterology Research and Practice No. 2013 (2013), pp.1-6.
https://search.emarefa.net/detail/BIM-463852
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Xia, X. M.& Wang, H.. Gastroesophageal Reflux Disease Relief in Patients Treated with Rabeprazole 20 mg versus Omeprazole 20 mg : A Meta-Analysis. Gastroenterology Research and Practice. 2013. Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-463852
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-463852
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
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