HPV 16 Is Related to the Progression of Cervical Intraepithelial Neoplasia Grade 2 : A Case Series
المؤلفون المشاركون
Andreoli, Maria Antonieta
Termini, Lara
Villa, Luisa Lina
Loffredo D’Ottaviano, Maria Gabriela
Costa, Maria Cecília
Discacciati, Michelle Garcia
Rabelo-Santos, Silvia H.
Zeferino, Luiz Carlos
المصدر
Obstetrics and Gynecology International
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-12-04
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
Purpose.
To describe the acquisition, persistence, and clearance of HPV infection in women with CIN 2 followed up for 12 months.
Methods.
Thirty-seven women with CIN 2 biopsy, who have proven referral to cervical smear showing low-grade squamous intraepithelial lesions or atypical squamous cells of undetermined significance and tested for HPV, were followed up for one year with cervical smear, colposcopy, and HPV test every three months.
HPV DNA was detected by the polymerase chain reaction and genotyping by reverse line blot hybridization assay.
Results.
CIN 2 regression rate was 49% (18/37), persistence as CIN 1 or CIN 2 was 22% (8/37), and progression to CIN 3 was 29% (11/37).
Multiple HPV types were observed at admission in 41% (15/37) of cases.
HPV 16 was detected at admission in 58% (11/19) of the cases that persisted/progressed and in 39% (7/18) of the cases that regressed.
HPV 16 was considered possibly causal in 67% (10/15) of the cases that persisted or progressed and in 10% (1/10) of the cases that regressed (P=0.01).
Conclusion.
Multiple HPV infections were frequently detected among women with CIN 2 at admission and during the followup.
The CIN 2 associated with HPV 16 was more likely to persist or to progress to CIN 3.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Loffredo D’Ottaviano, Maria Gabriela& Discacciati, Michelle Garcia& Andreoli, Maria Antonieta& Costa, Maria Cecília& Termini, Lara& Rabelo-Santos, Silvia H.…[et al.]. 2013. HPV 16 Is Related to the Progression of Cervical Intraepithelial Neoplasia Grade 2 : A Case Series. Obstetrics and Gynecology International،Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-463960
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Loffredo D’Ottaviano, Maria Gabriela…[et al.]. HPV 16 Is Related to the Progression of Cervical Intraepithelial Neoplasia Grade 2 : A Case Series. Obstetrics and Gynecology International No. 2013 (2013), pp.1-5.
https://search.emarefa.net/detail/BIM-463960
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Loffredo D’Ottaviano, Maria Gabriela& Discacciati, Michelle Garcia& Andreoli, Maria Antonieta& Costa, Maria Cecília& Termini, Lara& Rabelo-Santos, Silvia H.…[et al.]. HPV 16 Is Related to the Progression of Cervical Intraepithelial Neoplasia Grade 2 : A Case Series. Obstetrics and Gynecology International. 2013. Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-463960
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-463960
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر