Association between Peripheral Oxidative Stress and White Matter Damage in Acute Traumatic Brain Injury
المؤلفون المشاركون
Lin, Wei-Che
Wang, Hung-Chen
Chen, Pei-Chin
Kung, Chia-Te
Weng, Hsu-Huei
Chen, Meng-Hsiang
Li, Shau-Hsuan
Chen, Hsiu-Ling
Tsai, Nai-Wen
Lin, Wei-Ming
Lu, Cheng-Hsien
Su, Yu-Jih
Chiu, Tsui-Min
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-04-03
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
The oxidative stress is believed to be one of the mechanisms involved in the neuronal damage after acute traumatic brain injury (TBI).
However, the disease severity correlation between oxidative stress biomarker level and deep brain microstructural changes in acute TBI remains unknown.
In present study, twenty-four patients with acute TBI and 24 healthy volunteers underwent DTI.
The peripheral blood oxidative biomarkers, like serum thiol and thiobarbituric acid-reactive substances (TBARS) concentrations, were also obtained.
The DTI metrics of the deep brain regions, as well as the fractional anisotropy (FA) and apparent diffusion coefficient, were measured and correlated with disease severity, serum thiol, and TBARS levels.
We found that patients with TBI displayed lower FAs in deep brain regions with abundant WMs and further correlated with increased serum TBARS level.
Our study has shown a level of anatomic detail to the relationship between white matter (WM) damage and increased systemic oxidative stress in TBI which suggests common inflammatory processes that covary in both the peripheral and central reactions after TBI.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Lin, Wei-Ming& Chen, Meng-Hsiang& Wang, Hung-Chen& Lu, Cheng-Hsien& Chen, Pei-Chin& Chen, Hsiu-Ling…[et al.]. 2014. Association between Peripheral Oxidative Stress and White Matter Damage in Acute Traumatic Brain Injury. BioMed Research International،Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-464192
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Lin, Wei-Ming…[et al.]. Association between Peripheral Oxidative Stress and White Matter Damage in Acute Traumatic Brain Injury. BioMed Research International No. 2014 (2014), pp.1-8.
https://search.emarefa.net/detail/BIM-464192
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Lin, Wei-Ming& Chen, Meng-Hsiang& Wang, Hung-Chen& Lu, Cheng-Hsien& Chen, Pei-Chin& Chen, Hsiu-Ling…[et al.]. Association between Peripheral Oxidative Stress and White Matter Damage in Acute Traumatic Brain Injury. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-8.
https://search.emarefa.net/detail/BIM-464192
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-464192
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر