ATP Release from Mast Cells by Physical Stimulation : A Putative Early Step in Activation of Acupuncture Points
المؤلفون المشاركون
Hu, Lei
Schwarz, Wolfgang
Sikora, Jacek
Shen, Xueyong
Wang, Lina
Grygorczyk, Ryszard
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-06-04
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
In Chinese medicine acupuncture points are treated by physical stimuli to counteract various diseases.
These stimuli include mechanical stress as applied during the needle manipulation or tuina, high temperatures as applied during moxibustion, and red laser light applied during laser acupuncture.
This study aimed to investigate cellular responses to stimuli that might occur in the tissue of acupuncture points.
Since they have a characteristically high density of mast cells that degranulate in response to acupuncture, we asked whether these processes lead to ATP release.
We tested in in vitro experiments on mast cells of the human mast-cell line HMC-1 the effects of the physical stimuli; mechanical stress was applied by superfusion of the cells with hypotonic solution, heat was applied by incubation of the cells at 52°C, and red laser light of 657 nm was used for irradiation.
We demonstrate that all the stimuli induce ATP release from model human mast HMC-1 cells, and this release is associated with an intracellular free Ca2+ rise.
We hypothesize that ATP released from mast cells supplements the already known release of ATP from keratinocytes and, by acting on P2X receptors, it may serve as initial mediator of acupuncture-induced analgesia.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Wang, Lina& Sikora, Jacek& Hu, Lei& Shen, Xueyong& Grygorczyk, Ryszard& Schwarz, Wolfgang. 2013. ATP Release from Mast Cells by Physical Stimulation : A Putative Early Step in Activation of Acupuncture Points. Evidence-Based Complementary and Alternative Medicine،Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-464968
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Wang, Lina…[et al.]. ATP Release from Mast Cells by Physical Stimulation : A Putative Early Step in Activation of Acupuncture Points. Evidence-Based Complementary and Alternative Medicine No. 2013 (2013), pp.1-7.
https://search.emarefa.net/detail/BIM-464968
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Wang, Lina& Sikora, Jacek& Hu, Lei& Shen, Xueyong& Grygorczyk, Ryszard& Schwarz, Wolfgang. ATP Release from Mast Cells by Physical Stimulation : A Putative Early Step in Activation of Acupuncture Points. Evidence-Based Complementary and Alternative Medicine. 2013. Vol. 2013, no. 2013, pp.1-7.
https://search.emarefa.net/detail/BIM-464968
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-464968
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر