Dyspnea and Wheezing after Adenosine Injection in a Patient with Eosinophilic Bronchitis

الملخص EN

A 58-year-old nonsmoker female was referred for evaluation of chronic cough of 13 months duration.

After an initial work-up, the patient was diagnosed to have chronic cough due to eosinophilic bronchitis.

The diagnostic work-up for eosinophilic bronchitis and bronchial biopsy is discussed.

Eosinophilic bronchitis is differentiated from asthma.

In addition, the patient developed dyspnea, flushing, and wheezing after the administration of adenosine during a cardiac stress test in spite of a negative methacholine challenge.

This indirect stimulus of airway hyperresponsiveness suggests the possible involvement of mast cells in eosinophilic bronchitis.