Dilation of Malignant Strictures in Endoscopic Ultrasound Staging of Esophageal Cancer and Metastatic Spread of Disease

الملخص EN

Background.

Dilation of malignant strictures in endoscopic ultrasound (EUS) staging of esophageal cancer is safe, but no data exists regarding the subsequent development of metastases.

Aim.

Compare the rates of metastases in esophageal cancer patients undergoing EUS staging who require esophageal dilation in order to pass the echoendoscope versus those who do not.

Methods.

We reviewed consecutive patients referred for EUS staging of esophageal cancer.

We evaluated whether dilation was necessary in order to pass the echoendoscope, and for the subsequent development of metastases after EUS at various time intervals.

Results.

Among all patients with similar stage (locally advanced disease, defined as T3, N0, M0 or T1-3, N1, M0), there was no difference between the dilated and nondilated groups in the rates of metastases at 3 months (14% versus 10%), P=1.0, 6 months (28% versus 20%), P=0.69, 12 months (43% versus 40%), P=1.0, or ever during a mean followup of 15 months (71% versus 55%), P=0.48.

Conclusions.

Dilation of malignant strictures for EUS staging of esophageal cancer does not appear to lead to higher rates of distant metastases.