Comparison of Salivary TIMP-1 Levels in Periodontally Involved and Healthy Controls and the Response to Nonsurgical Periodontal Therapy
المؤلفون المشاركون
Fenol, Angel
Vyloppillil, Rajesh
Bhaskar, Anuradha
Perayil, Jayachandran
Peter, Maya Rajan
المصدر
International Journal of Chronic Diseases
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-02-06
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Background.
Periodontal disease is a chronic inflammatory condition affecting the supporting structures of the dentition.
Periodontal destruction is an outcome of the imbalance between matrix metalloproteinases and tissue inhibitors of matrix metalloproteinases (TIMPs).
We wanted to prove the hypothesis that salivary TIPM-1 level will vary in different people.
A decrease in TIMP-1 level could make them more susceptible to periodontitis whereas a normal level could prevent increased tissue destruction thereby inhibiting the progression from gingivitis to periodontitis.
This could probably pave the way for TIPM-1 to be a specific salivary biomarker and serve as a useful diagnostic and therapeutic tool in periodontitis.
Methods.
Whole unstimulated saliva of 2 ml was collected from twenty-five periodontally healthy and twenty-seven systemically healthy subjects with periodontitis.
Clinical parameters recorded at baseline and reevaluated after four weeks in subjects with periodontitis following nonsurgical periodontal therapy were gingival index (GI), oral hygiene index-Simplified (OHI-S), probing pocket depth, and clinical attachment level (CAL).
Salivary TIMP-1 levels in both were analyzed using a commercially available ELISA kit.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Fenol, Angel& Peter, Maya Rajan& Perayil, Jayachandran& Vyloppillil, Rajesh& Bhaskar, Anuradha. 2014. Comparison of Salivary TIMP-1 Levels in Periodontally Involved and Healthy Controls and the Response to Nonsurgical Periodontal Therapy. International Journal of Chronic Diseases،Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-466076
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Fenol, Angel…[et al.]. Comparison of Salivary TIMP-1 Levels in Periodontally Involved and Healthy Controls and the Response to Nonsurgical Periodontal Therapy. International Journal of Chronic Diseases No. 2014 (2014), pp.1-7.
https://search.emarefa.net/detail/BIM-466076
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Fenol, Angel& Peter, Maya Rajan& Perayil, Jayachandran& Vyloppillil, Rajesh& Bhaskar, Anuradha. Comparison of Salivary TIMP-1 Levels in Periodontally Involved and Healthy Controls and the Response to Nonsurgical Periodontal Therapy. International Journal of Chronic Diseases. 2014. Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-466076
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-466076
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر