Burkitt Lymphoma Presenting as Unilateral Deafness in an Immunocompetent Patient
المؤلفون المشاركون
Chapman-Fredericks, Jennifer
Pinto, Andre
Ikpatt, Offiong Francis
المصدر
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-09-25
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
A 55-year-old HIV-negative white male presented with right ear deafness, right axillary lymphadenopathy, and weight loss.
Laboratory findings included anemia, marked leukocytosis, and thrombocytopenia.
Examination of the peripheral smear demonstrated the presence of increased circulating blast-like cells of intermediate size, with basophilic cytoplasm and nuclei with open chromatin.
MRI of the brain was compatible with hemorrhagic labyrinthitis.
Excisional biopsy of the axillary mass revealed an enlarged lymph node with effaced architecture and “starry sky” appearance.
The cells expressed CD20, CD10, BCL6, and surface kappa immunoglobulin light chain, with a high proliferative index by immunohistochemistry and flow cytometry.
Subsequent bone marrow biopsy was hypercellular (approximately 95%), with blast-like cells virtually replacing all hematopoietic elements.
Routine karyotype as well as FISH analysis of bone marrow cells demonstrated rearrangement of the MYC gene at chromosome 8q24 region, IGH/MYC fusion, and additional signal for IGH gene.
We present herein a case of sporadic Burkitt lymphoma occurring in a previously healthy HIV-negative male.
The unusual clinical findings in this case include the relatively older age at presentation (55 years), an immunocompetent patient who had nodal involvement and leukemic phase of Burkitt, coupled with partial deafness.
A brief educational review of this neoplasm is made.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Pinto, Andre& Ikpatt, Offiong Francis& Chapman-Fredericks, Jennifer. 2012. Burkitt Lymphoma Presenting as Unilateral Deafness in an Immunocompetent Patient. Case Reports in Medicine،Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-466535
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Pinto, Andre…[et al.]. Burkitt Lymphoma Presenting as Unilateral Deafness in an Immunocompetent Patient. Case Reports in Medicine No. 2012 (2012), pp.1-5.
https://search.emarefa.net/detail/BIM-466535
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Pinto, Andre& Ikpatt, Offiong Francis& Chapman-Fredericks, Jennifer. Burkitt Lymphoma Presenting as Unilateral Deafness in an Immunocompetent Patient. Case Reports in Medicine. 2012. Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-466535
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-466535
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر