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Primary Acinic Cell Carcinoma of the Breast : A Clinicopathological and Immunohistochemical Study
المؤلفون المشاركون
Kaneko, Gengo
Shingu, Kiyoshi
Itoh, Nobuo
Ito, Tokiko
المصدر
Case Reports in Oncological Medicine
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-09-26
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
Acinic cell carcinoma of the breast is an extremely rare, malignant neoplasm characterized by widespread acinar cell-like differentiation and clinically low-grade malignancy.
Herein, we report a case of acinic cell carcinoma of the breast in a 41-year-old woman.
The tumor was poorly demarcated but had a firm consistency.
It was removed with lumpectomy, and sentinel lymph node biopsy was performed to check for metastasis.
Microscopically, the tumor showed an infiltrative growth pattern with a combination of solid, trabecular, and microglandular areas.
Many of the tumor cells had abundant clear vacuolated cytoplasm containing zymogen-typed granules which resemble acinar cells of the salivary glands.
The immunohistochemical profile of the tumor was also similar to that of salivary gland acinic cell carcinoma: the tumor cells were positive for amylase, lysozyme, α-1-antichymotrypsin, S-100 protein, and epithelial membrane antigen and negative for estrogen receptor, progesterone receptor, and human epidermal growth factor receptor 2.
She received postoperative chemoradiation therapy and has been well for 3 years since surgery.
As studies on large series are lacking, further studies are needed to elucidate the biological characteristics of acinic cell carcinoma of the breast.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Shingu, Kiyoshi& Ito, Tokiko& Kaneko, Gengo& Itoh, Nobuo. 2013. Primary Acinic Cell Carcinoma of the Breast : A Clinicopathological and Immunohistochemical Study. Case Reports in Oncological Medicine،Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-466893
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Shingu, Kiyoshi…[et al.]. Primary Acinic Cell Carcinoma of the Breast : A Clinicopathological and Immunohistochemical Study. Case Reports in Oncological Medicine No. 2013 (2013), pp.1-5.
https://search.emarefa.net/detail/BIM-466893
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Shingu, Kiyoshi& Ito, Tokiko& Kaneko, Gengo& Itoh, Nobuo. Primary Acinic Cell Carcinoma of the Breast : A Clinicopathological and Immunohistochemical Study. Case Reports in Oncological Medicine. 2013. Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-466893
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-466893
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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