![](/images/graphics-bg.png)
Oxidative Stress and Longevity in Okinawa : An Investigation of Blood Lipid Peroxidation and Tocopherol in Okinawan Centenarians
المؤلفون المشاركون
Willcox, Bradley J.
Willcox, Donald Craig
Rosenbaum, Matthew W.
Suzuki, Makoto
المصدر
Current Gerontology and Geriatrics Research
العدد
المجلد 2010، العدد 2010 (31 ديسمبر/كانون الأول 2010)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2011-03-30
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Background.
The Free Radical Theory of Aging mechanistically links oxidative stress to aging.
Okinawa has among the world's longest-lived populations but oxidative stress in this population has not been well characterized.
Methods.
We compared plasma lipid peroxide (LPO) and vitamin E—plasma and intracellular tocopherol levels (total α, β, and γ), in centenarians with younger controls.
Results.
Both LPO and vitamin E tocopherols were lower in centenarians, with the exception of intracellular β-tocopherol, which was significantly higher in centenarians versus younger controls.
There were no significant differences between age groups for tocopherol: cholesterol and tocopherol: LPO ratios.
Correlations were found between α-Tocopherol and LPO in septuagenarians but not in centenarians.
Conclusions.
The low plasma level of LPO in Okinawan centenarians, compared to younger controls, argues for protection against oxidative stress in the centenarian population and is consistent with the predictions of the Free Radical Theory of Aging.
However, the present work does not strongly support a role for vitamin E in this phenomenon.
The role of intracellular β-tocopherol deserves additional study.
More research is needed on the contribution of oxidative stress and antioxidants to human longevity.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Suzuki, Makoto& Willcox, Donald Craig& Rosenbaum, Matthew W.& Willcox, Bradley J.. 2011. Oxidative Stress and Longevity in Okinawa : An Investigation of Blood Lipid Peroxidation and Tocopherol in Okinawan Centenarians. Current Gerontology and Geriatrics Research،Vol. 2010, no. 2010, pp.1-10.
https://search.emarefa.net/detail/BIM-467486
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Suzuki, Makoto…[et al.]. Oxidative Stress and Longevity in Okinawa : An Investigation of Blood Lipid Peroxidation and Tocopherol in Okinawan Centenarians. Current Gerontology and Geriatrics Research No. 2010 (2010), pp.1-10.
https://search.emarefa.net/detail/BIM-467486
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Suzuki, Makoto& Willcox, Donald Craig& Rosenbaum, Matthew W.& Willcox, Bradley J.. Oxidative Stress and Longevity in Okinawa : An Investigation of Blood Lipid Peroxidation and Tocopherol in Okinawan Centenarians. Current Gerontology and Geriatrics Research. 2011. Vol. 2010, no. 2010, pp.1-10.
https://search.emarefa.net/detail/BIM-467486
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-467486
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
![](/images/ebook-kashef.png)
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
![](/images/kashef-image.png)