Large Cell Neuroendocrine Carcinoma of the Rectum Presenting with Extensive Metastatic Disease
المؤلفون المشاركون
Shuja, Sania
Eid, Emely
Minocha, Vinay
Ali, Robert
المصدر
Case Reports in Oncological Medicine
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-07-16
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
Introduction.
Rectal large cell neuroendocrine carcinoma (LCNEC) is a poorly differentiated neoplasm that is very rare and belongs within the poorest prognostic subgroup among primary colorectal neoplasms.
Here, we describe a case of LCNEC of the rectum, which highlights the aggressive clinical course and poor prognosis associated with this disease.
Case Presentation.
We report a case of a 63-year-old male who presented to our hospital with a one-month history of lower abdominal pain, constipation, and weight loss.
A computed tomography (CT) scan of the chest, abdomen, and pelvis revealed a rectal mass as well as metastatic disease of the liver and lung.
Flexible sigmoidoscopy revealed a fungating, ulcerated and partially obstructing rectal mass located 6 cm from the anal verge.
This mass was biopsied and pathological examination of the resected specimen revealed features consistent with a large cell neuroendocrine carcinoma.
Conclusion.
Rectal large cell neuroendocrine carcinomas are rare and have a significantly worse prognosis than adenocarcinomas.
At diagnosis, a higher stage and metastatic disease are likely to be found.
It is important to differentiate large cell, poorly differentiated neuroendocrine carcinomas from adenocarcinomas of the colon and rectum pathologically because patients may benefit from alternative cytotoxic chemotherapeutic regimens.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Minocha, Vinay& Shuja, Sania& Ali, Robert& Eid, Emely. 2014. Large Cell Neuroendocrine Carcinoma of the Rectum Presenting with Extensive Metastatic Disease. Case Reports in Oncological Medicine،Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-468023
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Minocha, Vinay…[et al.]. Large Cell Neuroendocrine Carcinoma of the Rectum Presenting with Extensive Metastatic Disease. Case Reports in Oncological Medicine No. 2014 (2014), pp.1-5.
https://search.emarefa.net/detail/BIM-468023
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Minocha, Vinay& Shuja, Sania& Ali, Robert& Eid, Emely. Large Cell Neuroendocrine Carcinoma of the Rectum Presenting with Extensive Metastatic Disease. Case Reports in Oncological Medicine. 2014. Vol. 2014, no. 2014, pp.1-5.
https://search.emarefa.net/detail/BIM-468023
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-468023
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر