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Determinants of Symptomatic Vulvovaginal Candidiasis among Human Immunodeficiency Virus Type 1 Infected Women in Rural KwaZulu-Natal, South Africa
المؤلفون المشاركون
Longo-Mbenza, Benjamin
Carr, William H.
Sturm, Willem A.
Apalata, Teke
Moodley, Prashini
المصدر
Infectious Diseases in Obstetrics and Gynecology
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-04-09
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Introduction.
We sought to determine the association between HIV-induced immunosuppression, virologic correlates, and vulvovaginal candidiasis (VVC).
Methods.
This is a retrospective cohort study, where HIV infected and uninfected women were studied with VVC being the primary outcome.
Ninety-seven HIV-infected and 101 HIV-uninfected women were enrolled between June and December 2011.
Cases of VVC were confirmed.
HIV RNA load was determined by RT-PCR and CD4 counts were obtained from medical records.
Results.
Fifty-two of 97 (53.6%) HIV-infected and 38/101 (37.6%) HIV-uninfected women were diagnosed with VVC (P=0.032).
The relative risk for VVC amongst HIV-infected patients was 1.53 (95% CI: 1.04–2 P=0.024).
Cases of VVC increased at CD4+ T cell count below 200 cells/mm3 (P<0.0001) and plasma HIV RNA load above 10 000 copies/mL (P<0.0001).
VVC was associated with increased genital shedding of HIV (P=0.002), and there was a linear correlation between plasma HIV load and genital HIV shedding (r=0.540; R2=0.292; P<0.0001).
Women on HAART were 4-fold less likely (P=0.029) to develop VVC.
Conclusion.
CD4 counts below 200 cells/mm3 and plasma HIV loads ≥10 000 copies/mL were significantly associated with VVC.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Apalata, Teke& Carr, William H.& Sturm, Willem A.& Longo-Mbenza, Benjamin& Moodley, Prashini. 2014. Determinants of Symptomatic Vulvovaginal Candidiasis among Human Immunodeficiency Virus Type 1 Infected Women in Rural KwaZulu-Natal, South Africa. Infectious Diseases in Obstetrics and Gynecology،Vol. 2014, no. 2014, pp.1-10.
https://search.emarefa.net/detail/BIM-468103
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Apalata, Teke…[et al.]. Determinants of Symptomatic Vulvovaginal Candidiasis among Human Immunodeficiency Virus Type 1 Infected Women in Rural KwaZulu-Natal, South Africa. Infectious Diseases in Obstetrics and Gynecology No. 2014 (2014), pp.1-10.
https://search.emarefa.net/detail/BIM-468103
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Apalata, Teke& Carr, William H.& Sturm, Willem A.& Longo-Mbenza, Benjamin& Moodley, Prashini. Determinants of Symptomatic Vulvovaginal Candidiasis among Human Immunodeficiency Virus Type 1 Infected Women in Rural KwaZulu-Natal, South Africa. Infectious Diseases in Obstetrics and Gynecology. 2014. Vol. 2014, no. 2014, pp.1-10.
https://search.emarefa.net/detail/BIM-468103
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-468103
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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