Change of Body Composition and Adipokines and Their Relationship with Insulin Resistance across Pubertal Development in Obese and Nonobese Chinese Children : The BCAMS Study
المؤلفون المشاركون
Zhao, Xiaoyuan
Li, Ming
Yin, Jinhua
Cheng, Hong
Xu, Lu
Yu, Miao
Xiao, Xin-Hua
Mi, Jie
المصدر
International Journal of Endocrinology
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-12-11
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
A transient increase in insulin resistance (IR) is a component of puberty.
We investigated the impact of body composition and adipokines on IR during puberty in Chinese children.
This study included 3223 schoolchildren aged 6–18 years.
IR was calculated using homeostasis model assessment (HOMA-IR).
We revealed that body mass index (BMI) and waist circumference increased gradually during puberty in both genders, while fat-mass percentage (FAT%) increased steadily only in girls.
Change of leptin showed striking sexual dimorphisms: in girls leptin increased steadily during puberty, whereas in boys, after a transient rise at the beginning of puberty, leptin declined by Tanner staging even in those overweight or obese.
Inversely, adiponectin level decreased significantly during puberty.
In both genders, HOMA-IR started to increase at the beginning of puberty, peaked in the middle, and revised at late puberty in overweight/obesity boys while it stayed high till the end of puberty in girls and normal weight boys.
Multivariate regression analysis revealed that leptin presented a stronger indicator of HOMA-IR than anthropometric measures during puberty.
Our results demonstrated that gender-specific FAT% and leptin changed with pubertal development.
Leptin emerged as a stronger predictor of IR than traditional anthropometric indices, suggesting a prominent role in the development of pubertal IR.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Xu, Lu& Li, Ming& Yin, Jinhua& Cheng, Hong& Yu, Miao& Zhao, Xiaoyuan…[et al.]. 2012. Change of Body Composition and Adipokines and Their Relationship with Insulin Resistance across Pubertal Development in Obese and Nonobese Chinese Children : The BCAMS Study. International Journal of Endocrinology،Vol. 2012, no. 2012, pp.1-10.
https://search.emarefa.net/detail/BIM-468198
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Xu, Lu…[et al.]. Change of Body Composition and Adipokines and Their Relationship with Insulin Resistance across Pubertal Development in Obese and Nonobese Chinese Children : The BCAMS Study. International Journal of Endocrinology No. 2012 (2012), pp.1-10.
https://search.emarefa.net/detail/BIM-468198
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Xu, Lu& Li, Ming& Yin, Jinhua& Cheng, Hong& Yu, Miao& Zhao, Xiaoyuan…[et al.]. Change of Body Composition and Adipokines and Their Relationship with Insulin Resistance across Pubertal Development in Obese and Nonobese Chinese Children : The BCAMS Study. International Journal of Endocrinology. 2012. Vol. 2012, no. 2012, pp.1-10.
https://search.emarefa.net/detail/BIM-468198
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-468198
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر