Intravenous Paracetamol Reduces Postoperative Opioid Consumption after Orthopedic Surgery : A Systematic Review of Clinical Trials
المؤلفون المشاركون
Baidya, Dalim Kumar
Khanna, Puneet
Maitra, Souvik
Jebaraj, Bright
المصدر
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-11-06
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Postoperative pain management is one of the most challenging jobs in orthopedic surgical population as it comprises of patients from extremes of ages and with multiple comorbidities.
Though effective, opioids may contribute to serious adverse effects particularly in old age patients.
Intravenous paracetamol is widely used in the postoperative period with the hope that it may reduce opioid consumption and produce better pain relief.
A brief review of human clinical trials where intravenous paracetamol was compared with placebo or no treatment in postoperative period in orthopedic surgical population has been done here.
We found that four clinical trials reported that there is a significant reduction in postoperative opioid consumption.
When patients received an IV injection of 2 g propacetamol, reduction of morphine consumption up to 46% has been reported.
However, one study did not find any reduction of opioid requirement after spinal surgery in children and adolescent.
Four clinical trials reported better pain scores when paracetamol has been used, but other three trials denied.
We conclude that postoperative intravenous paracetamol is a safe and effective adjunct to opioid after orthopedic surgery, but at present there is no data to decide whether paracetamol reduces opioid related adverse effects or not.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Jebaraj, Bright& Maitra, Souvik& Baidya, Dalim Kumar& Khanna, Puneet. 2013. Intravenous Paracetamol Reduces Postoperative Opioid Consumption after Orthopedic Surgery : A Systematic Review of Clinical Trials. Pain Research and Treatment،Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-469205
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Jebaraj, Bright…[et al.]. Intravenous Paracetamol Reduces Postoperative Opioid Consumption after Orthopedic Surgery : A Systematic Review of Clinical Trials. Pain Research and Treatment No. 2013 (2013), pp.1-6.
https://search.emarefa.net/detail/BIM-469205
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Jebaraj, Bright& Maitra, Souvik& Baidya, Dalim Kumar& Khanna, Puneet. Intravenous Paracetamol Reduces Postoperative Opioid Consumption after Orthopedic Surgery : A Systematic Review of Clinical Trials. Pain Research and Treatment. 2013. Vol. 2013, no. 2013, pp.1-6.
https://search.emarefa.net/detail/BIM-469205
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-469205
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر