Impact of a Multimodal Antimicrobial Stewardship Program on Pseudomonas aeruginosa Susceptibility and Antimicrobial Use in the Intensive Care Unit Setting
المؤلفون المشاركون
Petros, Karen O.
Sarwari, Arif R.
Slain, Douglas
Palmer, H. Carlton
Moffett, Kathryn
McKnight, Richard L.
Wilson, Alison
Sager, Renee B.
Dedhia, Harakh V.
Mullett, Charles J.
Thomas, James M.
المصدر
Critical Care Research and Practice
العدد
المجلد 2011، العدد 2011 (31 ديسمبر/كانون الأول 2011)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2011-05-19
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
Objective.
To study the impact of our multimodal antibiotic stewardship program on Pseudomonas aeruginosa susceptibility and antibiotic use in the intensive care unit (ICU) setting.
Methods.
Our stewardship program employed the key tenants of published antimicrobial stewardship guidelines.
These included prospective audits with intervention and feedback, formulary restriction with preauthorization, educational conferences, guidelines for use, antimicrobial cycling, and de-escalation of therapy.
ICU antibiotic use was measured and expressed as defined daily doses (DDD) per 1,000 patient-days.
Results.
Certain temporal relationships between antibiotic use and ICU resistance patterns appeared to be affected by our antibiotic stewardship program.
In particular, the ICU use of intravenous ciprofloxacin and ceftazidime declined from 148 and 62.5 DDD/1,000 patient-days to 40.0 and 24.5, respectively, during 2004 to 2007.
An increase in the use of these agents and resistance to these agents was witnessed during 2008–2010.
Despite variability in antibiotic usage from the stewardship efforts, we were overall unable to show statistical relationships with P.
aeruginosa resistance rate.
Conclusion.
Antibiotic resistance in the ICU setting is complex.
Multimodal stewardship efforts attempt to prevent resistance, but such programs clearly have their limits.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Slain, Douglas& Sarwari, Arif R.& Petros, Karen O.& McKnight, Richard L.& Sager, Renee B.& Mullett, Charles J.…[et al.]. 2011. Impact of a Multimodal Antimicrobial Stewardship Program on Pseudomonas aeruginosa Susceptibility and Antimicrobial Use in the Intensive Care Unit Setting. Critical Care Research and Practice،Vol. 2011, no. 2011, pp.1-5.
https://search.emarefa.net/detail/BIM-470451
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Slain, Douglas…[et al.]. Impact of a Multimodal Antimicrobial Stewardship Program on Pseudomonas aeruginosa Susceptibility and Antimicrobial Use in the Intensive Care Unit Setting. Critical Care Research and Practice No. 2011 (2011), pp.1-5.
https://search.emarefa.net/detail/BIM-470451
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Slain, Douglas& Sarwari, Arif R.& Petros, Karen O.& McKnight, Richard L.& Sager, Renee B.& Mullett, Charles J.…[et al.]. Impact of a Multimodal Antimicrobial Stewardship Program on Pseudomonas aeruginosa Susceptibility and Antimicrobial Use in the Intensive Care Unit Setting. Critical Care Research and Practice. 2011. Vol. 2011, no. 2011, pp.1-5.
https://search.emarefa.net/detail/BIM-470451
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-470451
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر