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Biopolymeric Formulations for Biocatalysis and Biomedical Applications
المؤلفون المشاركون
Elnashar, Magdy M. M.
Kahil, Tarek
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-06-17
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Three gel disks formulations prepared using chitosan (Chito) or polyethylenimine (PEI) followed by glutaraldehyde were prepared for biocatalysis and biomedical applications.
The carriers have been used to immobilize lactase covalently and it was evaluated in terms of enzyme loading capacity and enzyme kinetics (km and Vmax).
The Km of the Chito formulation was almost half that of the PEI formulations, which is favored in industries.
On the other hand, the gel disks were evaluated in terms of their swelling kinetics and the gels’ morphology using SEM.
The mechanism of the three gels’ swelling was also studied and it was found to be non-Fickian, where the mechanism of transport depends on both the diffusion and polymer relaxation, which are controlling the overall rate of water uptake.
The Chito formulation was 2–5 folds and PEI formulations were 33–62 folds in terms of the swelling rate constant and the diffusion rate, respectively.
These results were highly supported by the SEM.
This study will help scientists to design the right polymer network for enzymes immobilization as well as control the surface area and the swelling power of the polymers for different applications such as drug delivery systems and tissue engineering.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Elnashar, Magdy M. M.& Kahil, Tarek. 2014. Biopolymeric Formulations for Biocatalysis and Biomedical Applications. BioMed Research International،Vol. 2014, no. 2014, pp.1-10.
https://search.emarefa.net/detail/BIM-470612
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Elnashar, Magdy M. M.& Kahil, Tarek. Biopolymeric Formulations for Biocatalysis and Biomedical Applications. BioMed Research International No. 2014 (2014), pp.1-10.
https://search.emarefa.net/detail/BIM-470612
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Elnashar, Magdy M. M.& Kahil, Tarek. Biopolymeric Formulations for Biocatalysis and Biomedical Applications. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-10.
https://search.emarefa.net/detail/BIM-470612
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-470612
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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