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Are Proteinase 3 and Cathepsin C Enzymes Related to Pathogenesis of Periodontitis?
المؤلفون المشاركون
Azarsız, Elif
Emingil, Gülnur
Kutukculer, Necil
Atilla, Gül
Türkoğlu, Oya
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-05-18
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Aim.
Cathepsin C is the activator of the polymorphonuclear leukocyte-derived proteinase 3, which contributes to inflammatory processes.
The aim of the present study was to investigate gingival crevicular fluid (GCF) proteinase 3 and cathepsin C levels in periodontal diseases.
Design.
Eighteen patients with chronic periodontitis (CP), 20 patients with generalized aggressive periodontitis (G-AgP), 20 patients with gingivitis, and 18 healthy subjects were included in the study.
Periodontal parameters including probing depth, clinical attachment level, papilla bleeding index, and plaque index were assessed in all study subjects.
GCF proteinase 3 and cathepsin C levels were analyzed by ELISA.
Results.
GCF proteinase 3 total amount was significantly higher in diseased groups compared to control group, after adjusting age P<0.05.
No differences were found in GCF cathepsin C levels among the study groups P>0.05.
Periodontal parameters of sampling sites were positively correlated with GCF proteinase 3 total amounts P<0.01 but not with cathepsin C total amounts P>0.05.
Conclusions.
Elevated levels of GCF proteinase 3 in CP, G-AgP, and gingivitis might suggest that proteinase 3 plays a role during inflammatory periodontal events in host response.
However, cathepsin C in GCF does not seem to have an effect on the pathogenesis of periodontal diseases.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Türkoğlu, Oya& Azarsız, Elif& Emingil, Gülnur& Kutukculer, Necil& Atilla, Gül. 2014. Are Proteinase 3 and Cathepsin C Enzymes Related to Pathogenesis of Periodontitis?. BioMed Research International،Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-470862
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Türkoğlu, Oya…[et al.]. Are Proteinase 3 and Cathepsin C Enzymes Related to Pathogenesis of Periodontitis?. BioMed Research International No. 2014 (2014), pp.1-7.
https://search.emarefa.net/detail/BIM-470862
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Türkoğlu, Oya& Azarsız, Elif& Emingil, Gülnur& Kutukculer, Necil& Atilla, Gül. Are Proteinase 3 and Cathepsin C Enzymes Related to Pathogenesis of Periodontitis?. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-470862
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-470862
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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