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Fibromyalgia Syndrome : Etiology, Pathogenesis, Diagnosis, and Treatment
المؤلفون المشاركون
Blonna, Davide
Marini, Eleonora
Castoldi, Filippo
Barbasetti, Nicola
Mattei, Lorenzo
Bonasia, Davide Edoardo
Bellato, Enrico
المصدر
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-17، 17ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-11-04
دولة النشر
مصر
عدد الصفحات
17
التخصصات الرئيسية
الملخص EN
Fibromyalgia syndrome is mainly characterized by pain, fatigue, and sleep disruption.
The etiology of fibromyalgia is still unclear: if central sensitization is considered to be the main mechanism involved, then many other factors, genetic, immunological, and hormonal, may play an important role.
The diagnosis is typically clinical (there are no laboratory abnormalities) and the physician must concentrate on pain and on its features.
Additional symptoms (e.g., Raynaud’s phenomenon, irritable bowel disease, and heat and cold intolerance) can be associated with this condition.
A careful differential diagnosis is mandatory: fibromyalgia is not a diagnosis of exclusion.
Since 1990, diagnosis has been principally based on the two major diagnostic criteria defined by the ACR.
Recently, new criteria have been proposed.
The main goals of the treatment are to alleviate pain, increase restorative sleep, and improve physical function.
A multidisciplinary approach is optimal.
While most nonsteroidal anti-inflammatory drugs and opioids have limited benefit, an important role is played by antidepressants and neuromodulating antiepileptics: currently duloxetine (NNT for a 30% pain reduction 7.2), milnacipran (NNT 19), and pregabalin (NNT 8.6) are the only drugs approved by the US Food and Drug Administration for the treatment of fibromyalgia.
In addition, nonpharmacological treatments should be associated with drug therapy.Erratum to “Fibromyalgia Syndrome: Etiology, Pathogenesis, Diagnosis, and Treatment”dx.doi.org/10.1155/2013/960270
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Bellato, Enrico& Marini, Eleonora& Castoldi, Filippo& Barbasetti, Nicola& Mattei, Lorenzo& Bonasia, Davide Edoardo…[et al.]. 2012. Fibromyalgia Syndrome : Etiology, Pathogenesis, Diagnosis, and Treatment. Pain Research and Treatment،Vol. 2012, no. 2012, pp.1-17.
https://search.emarefa.net/detail/BIM-471252
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Bellato, Enrico…[et al.]. Fibromyalgia Syndrome : Etiology, Pathogenesis, Diagnosis, and Treatment. Pain Research and Treatment No. 2012 (2012), pp.1-17.
https://search.emarefa.net/detail/BIM-471252
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Bellato, Enrico& Marini, Eleonora& Castoldi, Filippo& Barbasetti, Nicola& Mattei, Lorenzo& Bonasia, Davide Edoardo…[et al.]. Fibromyalgia Syndrome : Etiology, Pathogenesis, Diagnosis, and Treatment. Pain Research and Treatment. 2012. Vol. 2012, no. 2012, pp.1-17.
https://search.emarefa.net/detail/BIM-471252
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-471252
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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