Melanocyte Colonization and Pigmentation of Breast Carcinoma : Pathological and Clinical Aspects

الملخص EN

Introduction.

Melanocyte colonization of breast carcinoma by nonneoplastic melanocytes of epidermal origin is a rare and serious condition first described in 1977.

We report on the exceptional clinical and pathological features of this migration phenomenon in a 74-year-old patient.

Discussion.

The pathogenesis by which melanocyte migration takes place is not known, but a breached basement membrane is considered essential.

Conclusion.

Histological examination and additional staining of skin are essential to differentiate breast cancer melanosis from malignant melanoma.