Maternal Aerobic Exercise during Pregnancy Can Increase Spatial Learning by Affecting Leptin Expression on Offspring's Early and Late Period in Life Depending on Gender
المؤلفون المشاركون
Tugyan, Kazim
Dayi, Ayfer
Pekcetin, Cetın
Cingoz, Sultan
Kayatekin, Berkant Muammer
Çetin, Ferihan
Aksu, Ilkay
Ozbal, Seda
Uysal, Nazan
Agilkaya, Sinem
Gencoglu, Celal
المصدر
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-09-16
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
العلوم الطبيعية والحياتية (متداخلة التخصصات)
الطب البشري
تكنولوجيا المعلومات وعلم الحاسوب
الملخص EN
Maternal exercise during pregnancy has been suggested to exert beneficial effects on brain functions of the offspring.
Leptin is an adipocytokine which is secreted from adipose tissues and has positive effects on learning, memory, and synaptic plasticity.
In this study, pregnant rats were moderately exercised and we observed the effects of this aerobic exercise on their prepubertal and adult offsprings' spatial learning, hippocampal neurogenesis, and expression of leptin.
All the pups whose mothers exercised during pregnancy learned the platform earlier and spent longer time in the target quadrant.
Their thigmotaxis times were shorter than those measured in the control group.
It is shown that hippocampal CA1, CA3 neuron numbers increased in both prepubertal and adult pups, in addition that GD neuron numbers increased in adult pups.
Leptin receptor expression significantly increased in the prepubertal male, adult male, and adult female pups.
In our study, maternal running during pregnancy resulted in significant increase in the expression of leptin receptor but not in prepubertal female pups, enhanced hippocampal cell survival, and improved learning memory capability in prepubertal and adult rat pups, as compared to the control group.
In conclusion, maternal exercise during pregnancy may regulate spatial plasticity in the hippocampus of the offspring by increasing the expression of leptin.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Dayi, Ayfer& Agilkaya, Sinem& Ozbal, Seda& Çetin, Ferihan& Aksu, Ilkay& Gencoglu, Celal…[et al.]. 2012. Maternal Aerobic Exercise during Pregnancy Can Increase Spatial Learning by Affecting Leptin Expression on Offspring's Early and Late Period in Life Depending on Gender. The Scientific World Journal،Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-471619
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Dayi, Ayfer…[et al.]. Maternal Aerobic Exercise during Pregnancy Can Increase Spatial Learning by Affecting Leptin Expression on Offspring's Early and Late Period in Life Depending on Gender. The Scientific World Journal No. 2012 (2012), pp.1-8.
https://search.emarefa.net/detail/BIM-471619
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Dayi, Ayfer& Agilkaya, Sinem& Ozbal, Seda& Çetin, Ferihan& Aksu, Ilkay& Gencoglu, Celal…[et al.]. Maternal Aerobic Exercise during Pregnancy Can Increase Spatial Learning by Affecting Leptin Expression on Offspring's Early and Late Period in Life Depending on Gender. The Scientific World Journal. 2012. Vol. 2012, no. 2012, pp.1-8.
https://search.emarefa.net/detail/BIM-471619
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-471619
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر