Vitamin D in Early Childhood and the Effect on Immunity to Mycobacterium tuberculosis
المؤلفون المشاركون
Burl, Sarah
Kampmann, Beate
Battersby, Anna Jane
المصدر
Clinical and Developmental Immunology
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-07-05
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
A potential role for vitamin D as a therapeutic immunomodulator in tuberculosis (TB) has been recognised for over 150 years, but has only recently returned to the centre of the research arena due to the increasing awareness of the global vitamin D deficiency epidemic.
As early as birth a child is often deficient in vitamin D, which may not only affect their bone metabolism but also modulate their immune function, contributing to the increased susceptibility to many infections seen early in life.
Recent studies have begun to explain the mechanisms by which vitamin D affects immunity.
Antimicrobial peptides are induced in conjunction with stimulation of innate pattern recognition receptors enhancing immunity to particular infections.
In contrast the role of vitamin D within the adaptive immune response appears to be more regulatory in function, perhaps as a mechanism to reduce unwanted inflammation.
In this paper we focus on the effect of vitamin D on immunity to TB.
Where much of the attention has been paid by past reviews to the role of vitamin D in adult TB patients, this paper, where possible, focuses on research in paediatric populations.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Battersby, Anna Jane& Kampmann, Beate& Burl, Sarah. 2012. Vitamin D in Early Childhood and the Effect on Immunity to Mycobacterium tuberculosis. Clinical and Developmental Immunology،Vol. 2012, no. 2012, pp.1-10.
https://search.emarefa.net/detail/BIM-471717
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Battersby, Anna Jane…[et al.]. Vitamin D in Early Childhood and the Effect on Immunity to Mycobacterium tuberculosis. Clinical and Developmental Immunology No. 2012 (2012), pp.1-10.
https://search.emarefa.net/detail/BIM-471717
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Battersby, Anna Jane& Kampmann, Beate& Burl, Sarah. Vitamin D in Early Childhood and the Effect on Immunity to Mycobacterium tuberculosis. Clinical and Developmental Immunology. 2012. Vol. 2012, no. 2012, pp.1-10.
https://search.emarefa.net/detail/BIM-471717
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-471717
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر