The Influence of Long Term Hydrochlorothiazide Administration on the Relationship between Renin-Angiotensin-Aldosterone System Activity and Plasma Glucose in Patients with Hypertension
المؤلفون المشاركون
Xiao, Xu
Hu, Wei-jian
Shaw, Peter X.
Du, Hong-jun
المصدر
Oxidative Medicine and Cellular Longevity
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-11-19
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
العلوم الطبيعية والحياتية (متداخلة التخصصات)
الأحياء
الملخص EN
Objective.
To observe the relationship between changes in renin-angiotensin-aldosterone system (RAAS) activity and blood plasma glucose after administration of hydrochlorothiazide (HCTZ) for one year in patients with hypertension.
Methods.
108 hypertensive patients were given 12.5 mg HCTZ per day for one year.
RAAS activity, plasma glucose levels, and other biochemical parameters, as well as plasma oxidized low density lipoprotein (oxLDL) levels, were measured and analyzed at baseline, six weeks, and one year after treatment.
Results.
After one year of treatment, the reduction in plasma glucose observed between the elevated plasma renin activity (PRA) group (-0.26±0.26 mmol/L) and the nonelevated PRA group (-1.36±0.23 mmol/L) was statistically significant (P<0.05).
The decrease of plasma glucose in the elevated Ang II group (-0.17±0.18 mmol/L) compared to the nonelevated Ang II group (-1.07±0.21 mmol/L) was statistically significant (P<0.05).
The proportion of patients with elevated plasma glucose in the elevated Ang II group (40.5%) was significantly higher than those in the nonelevated Ang II group (16.3%) (P<0.05).
The relative oxLDL level was not affected by the treatment.
Conclusions.
Changes in RAAS activity were correlated with changes in plasma glucose levels after one year of HCTZ therapy.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Xiao, Xu& Du, Hong-jun& Hu, Wei-jian& Shaw, Peter X.. 2013. The Influence of Long Term Hydrochlorothiazide Administration on the Relationship between Renin-Angiotensin-Aldosterone System Activity and Plasma Glucose in Patients with Hypertension. Oxidative Medicine and Cellular Longevity،Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-471954
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Xiao, Xu…[et al.]. The Influence of Long Term Hydrochlorothiazide Administration on the Relationship between Renin-Angiotensin-Aldosterone System Activity and Plasma Glucose in Patients with Hypertension. Oxidative Medicine and Cellular Longevity No. 2013 (2013), pp.1-5.
https://search.emarefa.net/detail/BIM-471954
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Xiao, Xu& Du, Hong-jun& Hu, Wei-jian& Shaw, Peter X.. The Influence of Long Term Hydrochlorothiazide Administration on the Relationship between Renin-Angiotensin-Aldosterone System Activity and Plasma Glucose in Patients with Hypertension. Oxidative Medicine and Cellular Longevity. 2013. Vol. 2013, no. 2013, pp.1-5.
https://search.emarefa.net/detail/BIM-471954
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-471954
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر