PPARγ : The Portrait of a Target Ally to Cancer Chemopreventive Agents

المؤلفون المشاركون

Sainis, Ioannis
Vareli, Katerina
Karavasilis, Vasilios
Briasoulis, Evangelos

المصدر

PPAR Research

العدد

المجلد 2008، العدد 2008 (31 ديسمبر/كانون الأول 2008)، ص ص. 1-10، 10ص.

الناشر

Hindawi Publishing Corporation

تاريخ النشر

2008-09-03

دولة النشر

مصر

عدد الصفحات

10

التخصصات الرئيسية

العلوم الطبيعية والحياتية (متداخلة التخصصات)
الأحياء

الملخص EN

Peroxisome proliferator-activated receptor-gamma (PPARγ), one of three ligand-activated transcription factors named PPAR, has been identified as a molecular target for cancer chemopreventive agents.

PPARγ was initially understood as a regulator of adipocyte differentiation and glucose homeostasis while later on, it became evident that it is also involved in cell differentiation, apoptosis, and angiogenesis, biological processes which are deregulated in cancer.

It is now established that PPARγ ligands can induce cell differentiation and yield early antineoplastic effects in several tumor types.

Moreover, several bioactive natural products with cancer protecting potential are shown to operate through activation of PPARγ.

Overall, PPARγ appears to be a prevalent target ally to cancer chemopreventive agents and therefore pursuing research in this area is of great relevance.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Sainis, Ioannis& Vareli, Katerina& Karavasilis, Vasilios& Briasoulis, Evangelos. 2008. PPARγ : The Portrait of a Target Ally to Cancer Chemopreventive Agents. PPAR Research،Vol. 2008, no. 2008, pp.1-10.
https://search.emarefa.net/detail/BIM-472148

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Sainis, Ioannis…[et al.]. PPARγ : The Portrait of a Target Ally to Cancer Chemopreventive Agents. PPAR Research No. 2008 (2008), pp.1-10.
https://search.emarefa.net/detail/BIM-472148

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Sainis, Ioannis& Vareli, Katerina& Karavasilis, Vasilios& Briasoulis, Evangelos. PPARγ : The Portrait of a Target Ally to Cancer Chemopreventive Agents. PPAR Research. 2008. Vol. 2008, no. 2008, pp.1-10.
https://search.emarefa.net/detail/BIM-472148

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references

رقم السجل

BIM-472148