A Potential Link between Environmental Triggers and Autoimmunity
المؤلف
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-18، 18ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-02-12
دولة النشر
مصر
عدد الصفحات
18
التخصصات الرئيسية
الملخص EN
Autoimmune diseases have registered an alarming rise worldwide in recent years.
Accumulated evidence indicates that the immune system's ability to distinguish self from nonself is negatively impacted by genetic factors and environmental triggers.
Genetics is certainly a factor, but since it normally takes a very long time for the human genetic pattern to change enough to register on a worldwide scale, increasingly the attention of studies has been focused on the environmental factors of a rapidly changing and evolving civilization.
New technology, new industries, new inventions, new chemicals and drugs, and new foods and diets are constantly and rapidly being introduced in this fast-paced ever-changing world.
Toxicants, infections, epitope spreading, dysfunctions of immune homeostasis, and dietary components can all have an impact on the body's delicate immune recognition system.
Although the precise etiology and pathogenesis of many autoimmune diseases are still unknown, it would appear from the collated studies that there are common mechanisms in the immunopathogenesis of multiple autoimmune reactivities.
Of particular interest is the citrullination of host proteins and their conversion to autoantigens by the aforementioned environmental triggers.
The identification of these specific triggers of autoimmune reactivity is essential then for the development of new therapies for autoimmune diseases.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Vojdani, Aristo. 2014. A Potential Link between Environmental Triggers and Autoimmunity. Autoimmune Diseases،Vol. 2014, no. 2014, pp.1-18.
https://search.emarefa.net/detail/BIM-472234
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Vojdani, Aristo. A Potential Link between Environmental Triggers and Autoimmunity. Autoimmune Diseases No. 2014 (2014), pp.1-18.
https://search.emarefa.net/detail/BIM-472234
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Vojdani, Aristo. A Potential Link between Environmental Triggers and Autoimmunity. Autoimmune Diseases. 2014. Vol. 2014, no. 2014, pp.1-18.
https://search.emarefa.net/detail/BIM-472234
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-472234
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر