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Incidental Thyroid Carcinoma Diagnosed after Total Thyroidectomy for Benign Thyroid Diseases : Incidence and Association with Thyroid Disease Type and Laboratory Markers
المؤلفون المشاركون
Polychronidis, A.
Askitis, D.
Efraimidou, Eleni
Karanikas, M.
Lyratzopoulos, N.
Tripsianis, Grigorios
Mitrakas, A.
المصدر
International Journal of Endocrinology
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-11-20
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Objective.
Currently, total thyroidectomy (TT) is widely used to treat benign thyroid diseases and thyroid carcinoma.
The differential diagnosis between benign and malignant thyroid disorders and the potential identification of thyroid microcarcinomas with biochemical markers remain controversial.
This retrospective study aimed to estimate the prognostic validity of thyroid autoantibodies, thyroglobulin (Tg), and the thyroid disease type in diagnostic approaches regarding the co-existence of incidental thyroid carcinoma (ITC) with benign thyroid diseases.
Methods.
A cohort of 228 patients was treated with TT for benign thyroid disorders between 2005 and 2010.
Thyroid autoantibodies and Tg were preoperatively estimated.
Patients were classified according to the preoperative and histologically established diagnoses, and the median values of the biochemical markers were compared between the groups.
Results.
ITC was detected in 33/228 patients and almost exclusively in the presence of nontoxic thyroid disorders (P=0.014).
There were no statistically significant differences in the median values of the biochemical markers between the benign and malignant groups.
There was also no significant association between ITC and chronic lymphocytic thyroiditis.
Conclusions.
The co-existence of ITC with benign and especially nontoxic thyroid diseases is significant, and treatment of these disorders with TT when indicated can lead to the identification and definitive cure of microcarcinomas.
Further studies are required to establish precise markers with prognostic validity for TC diagnosis.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Askitis, D.& Efraimidou, Eleni& Karanikas, M.& Mitrakas, A.& Tripsianis, Grigorios& Polychronidis, A.…[et al.]. 2013. Incidental Thyroid Carcinoma Diagnosed after Total Thyroidectomy for Benign Thyroid Diseases : Incidence and Association with Thyroid Disease Type and Laboratory Markers. International Journal of Endocrinology،Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-472673
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Askitis, D.…[et al.]. Incidental Thyroid Carcinoma Diagnosed after Total Thyroidectomy for Benign Thyroid Diseases : Incidence and Association with Thyroid Disease Type and Laboratory Markers. International Journal of Endocrinology No. 2013 (2013), pp.1-8.
https://search.emarefa.net/detail/BIM-472673
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Askitis, D.& Efraimidou, Eleni& Karanikas, M.& Mitrakas, A.& Tripsianis, Grigorios& Polychronidis, A.…[et al.]. Incidental Thyroid Carcinoma Diagnosed after Total Thyroidectomy for Benign Thyroid Diseases : Incidence and Association with Thyroid Disease Type and Laboratory Markers. International Journal of Endocrinology. 2013. Vol. 2013, no. 2013, pp.1-8.
https://search.emarefa.net/detail/BIM-472673
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-472673
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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