Phytochemical Analysis and Antioxidant Property of Leaf Extracts of Vitex doniana and Mucuna pruriens
المؤلفون المشاركون
المصدر
Biochemistry Research International
العدد
المجلد 2011، العدد 2011 (31 ديسمبر/كانون الأول 2011)، ص ص. 1-4، 4ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2011-04-18
دولة النشر
مصر
عدد الصفحات
4
التخصصات الرئيسية
الملخص EN
Oxidative stress and impaired antioxidant system have been implicated in the pathophysiology of diverse disease states.
The phytochemical screening and antioxidant property of fresh leaves of Vitex doniana and Mucuna pruriens, used in the management and treatment of various diseases, were studied.
The extracts (ethanol and distilled water) were screened for the presence of phytochemicals, and their inhibition of 2,2-diphenyl-1-picryl-hydrazyl (DPPH) radical was used to evaluate their free radical scavenging activity.
Liver levels of malondialdehyde (MDA), superoxide dismutase (SOD), and catalase (CAT) in carbon tetrachloride- (CCl4) treated albino rats were also used to assess the antioxidant activity of the extracts.
The animals were treated with 250 mg/kg body weight of the extracts for six consecutive days before a single dose (2.5 mL/kg body weight) of CCl4.
Vitamin C was used as the standard antioxidant.
Phytochemical screening revealed the presence of saponins, tannins, anthraquinones, terpenoids, and flavonoids in all the extracts, while alkaloids were detected in extracts of Vitex doniana only, and cardiac glycosides occurred in extracts of Mucuna pruriens only.
All the extracts inhibited DPPH radical in a concentration-dependent manner, water extract of Vitex doniana producing highest inhibition which was not significantly different (P>.05) from vitamin C.
The extracts produced a significant decrease (P<.05) in liver MDA, while the levels of SOD and CAT significantly increased (P<.05) relative to the positive control.
These results are an indication of antioxidant potential of the extracts and may be responsible for some of the therapeutic uses of these plants.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Agbafor, K. N.& Nwachukwu, N.. 2011. Phytochemical Analysis and Antioxidant Property of Leaf Extracts of Vitex doniana and Mucuna pruriens. Biochemistry Research International،Vol. 2011, no. 2011, pp.1-4.
https://search.emarefa.net/detail/BIM-473268
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Agbafor, K. N.& Nwachukwu, N.. Phytochemical Analysis and Antioxidant Property of Leaf Extracts of Vitex doniana and Mucuna pruriens. Biochemistry Research International No. 2011 (2011), pp.1-4.
https://search.emarefa.net/detail/BIM-473268
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Agbafor, K. N.& Nwachukwu, N.. Phytochemical Analysis and Antioxidant Property of Leaf Extracts of Vitex doniana and Mucuna pruriens. Biochemistry Research International. 2011. Vol. 2011, no. 2011, pp.1-4.
https://search.emarefa.net/detail/BIM-473268
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-473268
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر