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Gastrointestinal Hemorrhage in Warfarin Anticoagulated Patients : Incidence, Risk Factor, Management, and Outcome
المؤلفون المشاركون
Cheng, Jin-Shiung
Tsay, Feng-Woei
Lai, Kwok-Hung
Chen, Wen-Chih
Chan, Hoi-Hung
Chen, Yan-Hua
Hsu, Ping-I
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-05-29
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Background.
Warfarin reduces the incidence of thromboembolism but increases the risk of gastrointestinal bleeding (GIB).
GIB during warfarin anticoagulation is rarely evaluated in Asian patients.
Aims.
This study aimed at investigating the incidence, risk factors, management, and outcome of GIB in Taiwanese patients treated with warfarin.
Methods.
We analyzed a cohort of warfarin anticoagulated patients between July 1993 and May 2012.
Clinical data were retrieved in a chart-reviewing manner.
Results.
A total of 401 warfarin anticoagulated patients were enrolled.
The incidence of GIB was 3.9% per patient-years.
Multivariate analysis with Cox regression showed that age >65 years old (RR: 2.5, 95% CI: 1.2–5.5), a mean international normalized ratio >2.1 (RR: 2.1, 95% CI: 1.0–4.2), a history of GIB (RR: 5.1, 95% CI: 1.9–13.5), and cirrhosis (RR: 6.9, 95% CI: 2.0–24.5) were independent factors predicting GIB.
27.3% of the GIB patients had rebleeding after restarting warfarin while thromboembolic events were found in 16.7% of the patients discontinuing warfarin therapy.
Conclusions.
Warfarin was associated with a significant incidence of GIB in Taiwanese patients.
The intensity of anticoagulation should be monitored closely during warfarin therapy, especially in patients with risk factors of GIB.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Chen, Wen-Chih& Chen, Yan-Hua& Hsu, Ping-I& Tsay, Feng-Woei& Chan, Hoi-Hung& Cheng, Jin-Shiung…[et al.]. 2014. Gastrointestinal Hemorrhage in Warfarin Anticoagulated Patients : Incidence, Risk Factor, Management, and Outcome. BioMed Research International،Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-473604
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Chen, Wen-Chih…[et al.]. Gastrointestinal Hemorrhage in Warfarin Anticoagulated Patients : Incidence, Risk Factor, Management, and Outcome. BioMed Research International No. 2014 (2014), pp.1-7.
https://search.emarefa.net/detail/BIM-473604
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Chen, Wen-Chih& Chen, Yan-Hua& Hsu, Ping-I& Tsay, Feng-Woei& Chan, Hoi-Hung& Cheng, Jin-Shiung…[et al.]. Gastrointestinal Hemorrhage in Warfarin Anticoagulated Patients : Incidence, Risk Factor, Management, and Outcome. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-7.
https://search.emarefa.net/detail/BIM-473604
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-473604
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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