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Concomitant Radiotherapy and Chemotherapy for High-Risk Nonmelanoma Skin Carcinomas of the Head and Neck
المؤلفون المشاركون
Shockley, William W.
Hayes, D. Neil
Dhruva, Nirav
Shores, Carol G.
Ardeshirpour, Farhad
Apisarnthanarax, Smith
Tepper, Joel E.
Rosenman, Julian G.
Hayward, Michele C.
المصدر
International Journal of Surgical Oncology
العدد
المجلد 2011، العدد 2011 (31 ديسمبر/كانون الأول 2011)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2011-09-25
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Background.
To report on the use and feasibility of a multimodality approach using concomitant radiotherapy and chemotherapy in patients with high-risk nonmelanoma skin carcinoma (NMSC) of the head and neck.
Methods.
Records of patients with NMSC of the head and neck who received concomitant CRT at the University of North Carolina between 2001 and 2007 were reviewed.
Results.
Fifteen identified patients had at least one of the following high-risk factors: T4 disease (93%), unresectability (60%), regional nodal involvement (40%), and/or recurrence (47%).
Ten patients were treated in the definitive setting and five in the postoperative setting.
Platinum based chemotherapy was given in 14 (93%) patients.
Ten of fifteen (67%) patients completed all planned chemotherapy treatments, and thirteen patients (87%) completed at least 80% of planned chemotherapy.
Mild radiation dermatitis occurred in all patients and reached grade 3 in 13% of patients.
No patients experienced grade 4 or 5 toxicity.
With a median followup of 31 months in surviving patients, the 2-year actuarial locoregional control and relapse-free survival were 79% and 49%, respectively.
Conclusions.
Definitive or postoperative chemoradiotherapy for patients with locally advanced or regionally metastasized NMSC of the head and neck appears feasible with acceptable toxicities and favorable locoregional control.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Apisarnthanarax, Smith& Dhruva, Nirav& Ardeshirpour, Farhad& Tepper, Joel E.& Shores, Carol G.& Rosenman, Julian G.…[et al.]. 2011. Concomitant Radiotherapy and Chemotherapy for High-Risk Nonmelanoma Skin Carcinomas of the Head and Neck. International Journal of Surgical Oncology،Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-473684
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Apisarnthanarax, Smith…[et al.]. Concomitant Radiotherapy and Chemotherapy for High-Risk Nonmelanoma Skin Carcinomas of the Head and Neck. International Journal of Surgical Oncology No. 2011 (2011), pp.1-8.
https://search.emarefa.net/detail/BIM-473684
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Apisarnthanarax, Smith& Dhruva, Nirav& Ardeshirpour, Farhad& Tepper, Joel E.& Shores, Carol G.& Rosenman, Julian G.…[et al.]. Concomitant Radiotherapy and Chemotherapy for High-Risk Nonmelanoma Skin Carcinomas of the Head and Neck. International Journal of Surgical Oncology. 2011. Vol. 2011, no. 2011, pp.1-8.
https://search.emarefa.net/detail/BIM-473684
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-473684
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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