Image-Guided Hypofractionated Radiotherapy in Low-Risk Prostate Cancer Patients
المؤلفون المشاركون
Enrici, Riccardo Maurizi
Agolli, Linda
Montalto, Adelaide
Bonome, Paolo
Minniti, Giuseppe
Carnevale, Alessia
De Sanctis, Vitaliana
Osti, Mattia F.
Valeriani, Maurizio
Nicosia, Luca
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-04-23
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Aim.
To evaluate efficacy and toxicity of image-guided hypofractionated radiotherapy (HFRT) in the treatment of low-risk prostate cancer.
Outcomes and toxicities of this series of patients were compared to another group of 32 low-risk patients treated with conventional fractionation (CFRT).
Methods.
Fifty-nine patients with low-risk prostate cancer were analysed.
Total dose for the prostate and proximal seminal vesicles was 60 Gy delivered in 20 fractions.
Results.
The median follow-up was 30 months.
The actuarial 4-year overall survival, biochemical free survival, and disease specific survival were 100%, 97.4%, and 97.4%, respectively.
Acute grade 1-2 gastrointestinal (GI) and genitourinary (GU) toxicity rates were 11.9% and 40.7%, respectively.
Grade 1 GI and GU late toxicity rates were 8.5% and 13.6%, respectively.
No grade ≥2 late toxicities were recorded.
Acute grade 2-3 GU toxicity resulted significantly lower (P=0.04) in HFRT group compared to the CFRT group.
The cumulative 4-year incidence of grade 1-2 GU toxicity was significantly higher (P<0.001) for HFRT patients.
Conclusions.
Our study demonstrated that hypofractionated regimen provided excellent biochemical control in favorable risk prostate cancer patients.
The incidence of GI and GU toxicity was low.
However, HFRT presented higher cumulative incidence of low-grade late GU toxicity than CFRT.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Valeriani, Maurizio& Carnevale, Alessia& Agolli, Linda& Bonome, Paolo& Montalto, Adelaide& Nicosia, Luca…[et al.]. 2014. Image-Guided Hypofractionated Radiotherapy in Low-Risk Prostate Cancer Patients. BioMed Research International،Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-473710
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Valeriani, Maurizio…[et al.]. Image-Guided Hypofractionated Radiotherapy in Low-Risk Prostate Cancer Patients. BioMed Research International No. 2014 (2014), pp.1-6.
https://search.emarefa.net/detail/BIM-473710
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Valeriani, Maurizio& Carnevale, Alessia& Agolli, Linda& Bonome, Paolo& Montalto, Adelaide& Nicosia, Luca…[et al.]. Image-Guided Hypofractionated Radiotherapy in Low-Risk Prostate Cancer Patients. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-6.
https://search.emarefa.net/detail/BIM-473710
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-473710
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر