Major Depressive Disorder and Measures of Cellular Aging : An Integrative Review
المؤلفون المشاركون
Kinser, Patricia Anne
Lyon, Debra E.
المصدر
العدد
المجلد 2013، العدد 2013 (31 ديسمبر/كانون الأول 2013)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2013-04-14
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Major depressive disorder (MDD) affects millions of individuals and causes significant suffering worldwide.
It has been speculated that MDD is associated with accelerated aging-related biological and functional decline.
To examine the accelerated aging hypothesis, one of the biomarkers under study is leukocyte telomeres, and specifically the measure of telomere length and telomerase activity.
This review integrates findings from eleven human studies which evaluated telomere length and telomerase activity, in order to synthesize the state of the current science and to inform the development of new knowledge and enhance nursing research of depression using appropriate biobehavioral measures.
Although preliminary, the findings from this integrated review suggest that there is evidence to support a conceptualization of depression as a stress-related condition in which telomeres shorten over time in relation to cumulative exposure to the chronic stress of depression.
For the purposes of testing in future nursing research, visual representations of the theoretical connection between stress vulnerabilities, depression, and health outcomes and key moderators and mediators involved in this conceptualization are provided.
The findings from this review and the conceptual framework provided may be a useful step towards advancing therapeutic nursing interventions for this debilitating chronic condition.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Kinser, Patricia Anne& Lyon, Debra E.. 2013. Major Depressive Disorder and Measures of Cellular Aging : An Integrative Review. Nursing Research and Practice،Vol. 2013, no. 2013, pp.1-10.
https://search.emarefa.net/detail/BIM-473942
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Kinser, Patricia Anne& Lyon, Debra E.. Major Depressive Disorder and Measures of Cellular Aging : An Integrative Review. Nursing Research and Practice No. 2013 (2013), pp.1-10.
https://search.emarefa.net/detail/BIM-473942
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Kinser, Patricia Anne& Lyon, Debra E.. Major Depressive Disorder and Measures of Cellular Aging : An Integrative Review. Nursing Research and Practice. 2013. Vol. 2013, no. 2013, pp.1-10.
https://search.emarefa.net/detail/BIM-473942
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-473942
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر