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Nanoparticulate Adjuvants and Delivery Systems for Allergen Immunotherapy
المؤلفون المشاركون
Ferrer, Marta
Irache, Juan Manuel
Sanz, María Luisa
Esparza, Irene
De Souza Rebouças, Juliana
Gamazo, Carlos
المصدر
Journal of Biomedicine and Biotechnology
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-13، 13ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-02-26
دولة النشر
مصر
عدد الصفحات
13
التخصصات الرئيسية
الملخص EN
In the last decades, significant progress in research and clinics has been made to offer possible innovative therapeutics for the management of allergic diseases.
However, current allergen immunotherapy shows limitations concerning the long-term efficacy and safety due to local side effects and risk of anaphylaxis.
Thus, effective and safe vaccines with reduced dose of allergen have been developed using adjuvants.
Nevertheless, the use of adjuvants still has several disadvantages, which limits its use in human vaccines.
In this context, several novel adjuvants for allergen immunotherapy are currently being investigated and developed.
Currently, nanoparticles-based allergen-delivery systems have received much interest as potential adjuvants for allergen immunotherapy.
It has been demonstrated that the incorporation of allergens into a delivery system plays an important role in the efficacy of allergy vaccines.
Several nanoparticles-based delivery systems have been described, including biodegradable and nondegradable polymeric carriers.
Therefore, this paper provides an overview of the current adjuvants used for allergen immunotherapy.
Furthermore, nanoparticles-based allergen-delivery systems are focused as a novel and promising strategy for allergy vaccines.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
De Souza Rebouças, Juliana& Esparza, Irene& Ferrer, Marta& Sanz, María Luisa& Irache, Juan Manuel& Gamazo, Carlos. 2012. Nanoparticulate Adjuvants and Delivery Systems for Allergen Immunotherapy. Journal of Biomedicine and Biotechnology،Vol. 2012, no. 2012, pp.1-13.
https://search.emarefa.net/detail/BIM-474439
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
De Souza Rebouças, Juliana…[et al.]. Nanoparticulate Adjuvants and Delivery Systems for Allergen Immunotherapy. Journal of Biomedicine and Biotechnology No. 2012 (2012), pp.1-13.
https://search.emarefa.net/detail/BIM-474439
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
De Souza Rebouças, Juliana& Esparza, Irene& Ferrer, Marta& Sanz, María Luisa& Irache, Juan Manuel& Gamazo, Carlos. Nanoparticulate Adjuvants and Delivery Systems for Allergen Immunotherapy. Journal of Biomedicine and Biotechnology. 2012. Vol. 2012, no. 2012, pp.1-13.
https://search.emarefa.net/detail/BIM-474439
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-474439
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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