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Urinary Bisphenol A and Hypertension in a Multiethnic Sample of US Adults
المؤلفون المشاركون
Teppala, Srinivas
Shankar, Anoop
المصدر
Journal of Environmental and Public Health
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-01-27
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
Background.
Bisphenol A (BPA) is a common chemical used in the manufacture of polycarbonate plastics and epoxy resins, with >93% of US adults having detectable BPA levels in urine.
Recent animal studies have suggested that BPA exposure may have a role in several mechanisms involved in the development of hypertension, including weight gain, insulin resistance, thyroid dysfunction, endothelial dysfunction, and oxidative stress.
However, no previous human study has examined the association between markers of BPA exposure and hypertension.
Methods.
We examined urinary BPA levels in 1380 subjects from the National Health and Nutritional Examination Survey 2003-2004.
Main outcome-of-interest was hypertension, defined as blood pressure-reducing medication use and/or blood pressures >140/90 mm of Hg (n=580).
Results.
We observed a positive association between increasing levels of urinary BPA and hypertension independent of confounding factors such as age, gender, race/ethnicity, smoking, body mass index (BMI), diabetes mellitus and total serum cholesterol levels.
Compared to tertile 1 (referent), the multivariate-adjusted odds ratio (95% confidence interval) of hypertension associated with tertile 3 was 1.50 (1.12−2.00); P-trend = 0.007.
The association was consistently present in subgroup analyses by race/ethnicity, smoking status, BMI, and diabetes mellitus.
Conclusions.
Urinary BPA levels are associated with hypertension, independent of traditional risk factors.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Shankar, Anoop& Teppala, Srinivas. 2012. Urinary Bisphenol A and Hypertension in a Multiethnic Sample of US Adults. Journal of Environmental and Public Health،Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-475027
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Shankar, Anoop& Teppala, Srinivas. Urinary Bisphenol A and Hypertension in a Multiethnic Sample of US Adults. Journal of Environmental and Public Health No. 2012 (2012), pp.1-5.
https://search.emarefa.net/detail/BIM-475027
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Shankar, Anoop& Teppala, Srinivas. Urinary Bisphenol A and Hypertension in a Multiethnic Sample of US Adults. Journal of Environmental and Public Health. 2012. Vol. 2012, no. 2012, pp.1-5.
https://search.emarefa.net/detail/BIM-475027
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-475027
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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