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Assessment of the Safety and Efficacy of a Raft-Forming Alginate Reflux Suppressant (Liquid Gaviscon) for the Treatment of Heartburn during Pregnancy
المؤلفون المشاركون
Thomas, Edward C. M.
Swales, Valerie S.
Dettmar, Peter W.
Lindow, Stephen W.
Strugala, Vicki
Bassin, Julian
المصدر
ISRN Obstetrics and Gynecology
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-11-04
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Gastro-oesophageal reflux (GER) and the symptoms of heartburn and regurgitation are common in pregnancy.
These symptoms are transient and mostly resolve postpartum but have a negative impact on quality of life.
Here, we present a prospective clinical evaluation of the safety and efficacy of an alginate raft-forming oral suspension that is licensed for use in pregnancy.
The study was a multicentre, prospective, open-label, and baseline-controlled study of Liquid Gaviscon (LG) in the treatment of heartburn in pregnant women with current symptoms of heartburn and/or reflux requiring treatment (recruited 144).
The efficacy of the study medication was rated by the investigator (primary endpoint) and patient.
Treatment was deemed to be a success in 91% of patients as judged by the investigator (95% CI 85.0–95.3) and 90% (95% CI 84.1–94.8) when assessed by the patient themselves.
Very few adverse events or serious adverse events were reported that were considered to be related to the study medication, and these were consistent with the normal population incidences.
Serum sodium levels remained unchanged.
This prospective open-label study in a large number of pregnant women has shown that LG is both safe and highly efficacious in the treatment of heartburn and GER symptoms in pregnancy.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Strugala, Vicki& Bassin, Julian& Swales, Valerie S.& Lindow, Stephen W.& Dettmar, Peter W.& Thomas, Edward C. M.. 2012. Assessment of the Safety and Efficacy of a Raft-Forming Alginate Reflux Suppressant (Liquid Gaviscon) for the Treatment of Heartburn during Pregnancy. ISRN Obstetrics and Gynecology،Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-475043
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Strugala, Vicki…[et al.]. Assessment of the Safety and Efficacy of a Raft-Forming Alginate Reflux Suppressant (Liquid Gaviscon) for the Treatment of Heartburn during Pregnancy. ISRN Obstetrics and Gynecology No. 2012 (2012), pp.1-6.
https://search.emarefa.net/detail/BIM-475043
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Strugala, Vicki& Bassin, Julian& Swales, Valerie S.& Lindow, Stephen W.& Dettmar, Peter W.& Thomas, Edward C. M.. Assessment of the Safety and Efficacy of a Raft-Forming Alginate Reflux Suppressant (Liquid Gaviscon) for the Treatment of Heartburn during Pregnancy. ISRN Obstetrics and Gynecology. 2012. Vol. 2012, no. 2012, pp.1-6.
https://search.emarefa.net/detail/BIM-475043
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-475043
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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