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Swimming Exercise Changes Hemodynamic Responses Evoked by Blockade of Excitatory Amino Receptors in the Rostral Ventrolateral Medulla in Spontaneously Hypertensive Rats
المؤلفون المشاركون
Ogihara, Cristiana A.
Schoorlemmer, Gerhardus H. M.
Colombari, Eduardo
Giannocco, Gisele
Sato, Monica A.
Lopes, Oswaldo U.
Lazari, Maria de Fátima M.
المصدر
العدد
المجلد 2014، العدد 2014 (31 ديسمبر/كانون الأول 2014)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2014-02-18
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Exercise training reduces sympathetic activity in hypertensive humans and rats.
We hypothesized that the swimming exercise would change the neurotransmission in the rostral ventrolateral medulla (RVLM), a key region involved in sympathetic outflow, and hemodynamic control in spontaneously hypertensive rats (SHR) and Wistar-Kyoto (WKY) rats.
Bilateral injections of kynurenic acid (KYN) were carried out in the RVLM in sedentary- (S-) or exercised- (E-) SHR and WKY rats submitted to swimming for 6 weeks.
Rats were α-chloralose anesthetized and artificially ventilated, with Doppler flow probes around the lower abdominal aorta and superior mesenteric artery.
Injections into the RVLM were made before and after i.v.
L-NAME (nitric oxide synthase, NOS, inhibitor).
Injections of KYN into the RVLM elicited a major vasodilation in the hindlimb more than in the mesenteric artery in E-SHR compared to S-SHR, but similar decrease in arterial pressure was observed in both groups.
Injections of KYN into the RVLM after i.v.
L-NAME attenuated the hindlimb vasodilation evoked by KYN and increased the mesenteric vasodilation in E-SHR.
Swimming exercise can enhance the hindlimb vasodilation mediated by peripheral NO release, reducing the activation of neurons with EAA receptors in the RVLM in SHR.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Ogihara, Cristiana A.& Schoorlemmer, Gerhardus H. M.& Lazari, Maria de Fátima M.& Giannocco, Gisele& Lopes, Oswaldo U.& Colombari, Eduardo…[et al.]. 2014. Swimming Exercise Changes Hemodynamic Responses Evoked by Blockade of Excitatory Amino Receptors in the Rostral Ventrolateral Medulla in Spontaneously Hypertensive Rats. BioMed Research International،Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-475546
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Ogihara, Cristiana A.…[et al.]. Swimming Exercise Changes Hemodynamic Responses Evoked by Blockade of Excitatory Amino Receptors in the Rostral Ventrolateral Medulla in Spontaneously Hypertensive Rats. BioMed Research International No. 2014 (2014), pp.1-9.
https://search.emarefa.net/detail/BIM-475546
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Ogihara, Cristiana A.& Schoorlemmer, Gerhardus H. M.& Lazari, Maria de Fátima M.& Giannocco, Gisele& Lopes, Oswaldo U.& Colombari, Eduardo…[et al.]. Swimming Exercise Changes Hemodynamic Responses Evoked by Blockade of Excitatory Amino Receptors in the Rostral Ventrolateral Medulla in Spontaneously Hypertensive Rats. BioMed Research International. 2014. Vol. 2014, no. 2014, pp.1-9.
https://search.emarefa.net/detail/BIM-475546
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-475546
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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