Successful Treatment of Posttransplant EBV-Associated Lymphoma and Plasmacytoma Solely Localized to the CNS
المؤلفون المشاركون
Hansen, Per Boye
Nielsen, Signe Ledou
المصدر
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-4، 4ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2012-02-28
دولة النشر
مصر
عدد الصفحات
4
التخصصات الرئيسية
الملخص EN
Two patients with diabetic nephropathy were diagnosed with primary central nervous system posttransplant Epstein-Barr-virus-associated lymphoproliferative disorder (PTLD) 3 years after renal transplantation.
The histological diagnoses of the isolated brain tumors were diffuse large B-cell lymphoma and plasmacytoma.
Considerable co-morbidity precluded intensive chemotherapy.
The first patient with lymphoid CD20+ PTLD had a partial resection of her tumor performed.
She was treated with 4 weekly doses of rituximab, ganciclovir and prednisolone; the posttransplant immune suppression (tacrolimus) was reduced.
After 4 weeks of treatment a magnetic resonance imaging (MRI) demonstrated complete regression of the CNS lesion.
The patient continues to receive rituximab (every second month), valgangciclovir and low-dose prednisolone.
Twenty-two months after initiation of therapy, she is still in complete remission.
The second patient was only treated with craniospinal irradiation involving the medulla to the second cervical vertebra and valgangciclovir.
Moreover, the posttransplant immune suppression was reduced.
A new MRI two months after initiation of therapy showed a complete regression of the lesions in the CNS; this was again demonstrated by a MRI after 19 months.
These 2 cases illustrate interesting alternative treatments of PTLD.
To our knowledge, an EBV-associated PTLD of plasmacytic origin isolated to the CNS has never been described before.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Hansen, Per Boye& Nielsen, Signe Ledou. 2012. Successful Treatment of Posttransplant EBV-Associated Lymphoma and Plasmacytoma Solely Localized to the CNS. Case Reports in Hematology،Vol. 2012, no. 2012, pp.1-4.
https://search.emarefa.net/detail/BIM-476415
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Hansen, Per Boye& Nielsen, Signe Ledou. Successful Treatment of Posttransplant EBV-Associated Lymphoma and Plasmacytoma Solely Localized to the CNS. Case Reports in Hematology No. 2012 (2012), pp.1-4.
https://search.emarefa.net/detail/BIM-476415
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Hansen, Per Boye& Nielsen, Signe Ledou. Successful Treatment of Posttransplant EBV-Associated Lymphoma and Plasmacytoma Solely Localized to the CNS. Case Reports in Hematology. 2012. Vol. 2012, no. 2012, pp.1-4.
https://search.emarefa.net/detail/BIM-476415
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-476415
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر