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Differential Impact of Stress Reduction Programs upon Ambulatory Blood Pressure among African American Adolescents : Influences of Endothelin-1 Gene and Chronic Stress Exposure
المؤلفون المشاركون
Dong, Yanbin
Tingen, Martha S.
Barnes, Vernon A.
Treiber, Frank A.
Zhu, Haidong
Gregoski, Mathew J.
المصدر
International Journal of Hypertension
العدد
المجلد 2012، العدد 2012 (31 ديسمبر/كانون الأول 2012)، ص ص. 1-12، 12ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2011-11-24
دولة النشر
مصر
عدد الصفحات
12
التخصصات الرئيسية
الملخص EN
Stress-activated gene × environment interactions may contribute to individual variability in blood pressure reductions from behavioral interventions.
We investigated effects of endothelin-1 (ET-1) LYS198ASN SNP and discriminatory stress exposure upon impact of 12-week behavioral interventions upon ambulatory BP (ABP) among 162 prehypertensive African American adolescents.
Following genotyping, completion of questionnaire battery, and 24-hour ABP monitoring, participants were randomized to health education control (HEC), life skills training (LST), or breathing awareness meditation (BAM).
Postintervention ABP was obtained.
Significant three-way interactions on ABP changes indicated that among ET-1 SNP carriers, the only group to show reductions was BAM from low chronic stress environments.
Among ET-1 SNP noncarriers, under low chronic stress exposure, all approaches worked, especially BAM.
Among high stress exposure noncarriers, only BAM resulted in reductions.
If these preliminary findings are replicated via ancillary analyses of archival databases and then via efficacy trials, selection of behavioral prescriptions for prehypertensives will be edging closer to being guided by individual's underlying genetic and environmental factors incorporating the healthcare model of personalized preventive medicine.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Gregoski, Mathew J.& Barnes, Vernon A.& Tingen, Martha S.& Dong, Yanbin& Zhu, Haidong& Treiber, Frank A.. 2011. Differential Impact of Stress Reduction Programs upon Ambulatory Blood Pressure among African American Adolescents : Influences of Endothelin-1 Gene and Chronic Stress Exposure. International Journal of Hypertension،Vol. 2012, no. 2012, pp.1-12.
https://search.emarefa.net/detail/BIM-477389
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Gregoski, Mathew J.…[et al.]. Differential Impact of Stress Reduction Programs upon Ambulatory Blood Pressure among African American Adolescents : Influences of Endothelin-1 Gene and Chronic Stress Exposure. International Journal of Hypertension No. 2012 (2012), pp.1-12.
https://search.emarefa.net/detail/BIM-477389
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Gregoski, Mathew J.& Barnes, Vernon A.& Tingen, Martha S.& Dong, Yanbin& Zhu, Haidong& Treiber, Frank A.. Differential Impact of Stress Reduction Programs upon Ambulatory Blood Pressure among African American Adolescents : Influences of Endothelin-1 Gene and Chronic Stress Exposure. International Journal of Hypertension. 2011. Vol. 2012, no. 2012, pp.1-12.
https://search.emarefa.net/detail/BIM-477389
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-477389
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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